Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | KDM5C | P41229 | 2/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.34 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.34 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | FNTA | P49354 | 1/20 | 0.32 |
| ▸ | FNTB | P49356 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CASP2 | P42575 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.31 |
| ▸ | KDM6B | O15054 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15398166 | 0.86 | FAAH (0.43) | ALDH1A1RECQLFAAHGAAACHE | |
| SCHEMBL19115845 | 0.81 | ALDH1A1 (0.46) | ALDH1A1LMNASLC15A2KDM4EKDM5C | |
| SCHEMBL9967369 | 0.79 | MGAM (0.38) | ALDH1A1LMNAKDM4EKDM5CEGLN1 | |
| SCHEMBL17776266 | 0.79 | ALDH1A1 (0.56) | ALDH1A1LMNASLC15A2KDM4EKDM5C | |
| SCHEMBL12251398 | 0.78 | DNM1 (0.39) | ALDH1A1LMNASLC15A2KDM4EFAAH | |
| SCHEMBL24419878 | 0.77 | — | — | |
| SCHEMBL16217889 | 0.77 | ALDH1A1 (0.53) | ALDH1A1LMNASLC15A2KDM4EKDM5C | |
| SCHEMBL3273991 | 0.77 | FAAH (0.54) | ALDH1A1LMNASLC15A2KDM4EFAAH | |
| SCHEMBL7997866 | 0.76 | ALDH1A1 (0.46) | ALDH1A1LMNASLC15A2KDM4EKDM5C | |
| SCHEMBL2754572 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8445627-B2 | Alkylene-dicarboxylate-containing biodegradable poly(ester-amides) and methods of use | MEDIVAS, LLC (US) | 2013-05-21 | — | — | US | disclosed |
| US-20070287987-A1 | Alkylene-dicarboxylate-containing biodegradable poly(ester-amides) and methods of use | MEDIVAS, LLC (US) | 2007-12-13 | — | — | US | disclosed |