SCHEMBL9967369

SCHEMBL9967369

CNCNC(=O)CC(C)=O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGAM O43451 1/20 0.38
GAA P10253 1/20 0.38
SI P14410 1/20 0.38
MGAM2 Q2M2H8 1/20 0.38
HTT P42858 2/20 0.35
LMNA P02545 1/20 0.35
KDM4E B2RXH2 4/20 0.33
ALDH1A1 P00352 3/20 0.33
MAPT P10636 2/20 0.33
KDM5C P41229 2/20 0.33
EGLN1 Q9GZT9 2/20 0.33
PHF8 Q9UPP1 2/20 0.33
KDM2A Q9Y2K7 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
KDM6B O15054 1/20 0.33
TRPA1 O75762 1/20 0.32
HIF1A Q16665 2/20 0.31
MAPK1 P28482 1/20 0.31
MEN1 O00255 1/20 0.31
CYP1A2 P05177 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13392107 0.95 MGAM (0.35) MGAMGAASIMGAM2HTT
SCHEMBL13429466 0.88 MGAM (0.41) MGAMGAASIMGAM2HTT
SCHEMBL14560142 0.83
SCHEMBL14560141 0.83
SCHEMBL13219609 0.81 KDM4E (0.40) MGAMGAASIMGAM2HTT
SCHEMBL15745782 0.80 MGAM (0.43) MGAMGAASIMGAM2
SCHEMBL14340992 0.79 ALDH1A1 (0.50) GAALMNAKDM4EALDH1A1KDM5C
SCHEMBL18174484 0.79 KDM4E (0.41) MGAMGAASIMGAM2HTT
SCHEMBL13219606 0.79 MEN1 (0.48) MGAMGAASIMGAM2HTT
SCHEMBL21546113 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11758909-B2 Antimicrobial nonwoven polyamides with zinc content ASCEND PERFORMANCE MATERIALS OPERATIONS LLC (US) 2023-09-19 US disclosed
US-11674247-B2 Polyamide nanofiber nonwovens ASCEND PERFORMANCE MATERIALS OPERATIONS LLC (US) 2023-06-13 US disclosed
US-20180201732-A1 Dynamic Cross-Linked Poly (Amides) Prepared Via The Incorporation Of Polyamines/Ammonium Salts In The Solid State SABIC GLOBAL TECHNOLOGIES B.V. (NP) 2018-07-19 US disclosed
US-20180163239-A1 EXPRESSION OF RECOMBINANT TETRACYCLINE EFFLUX PUMPS FOR THE PRODUCTION OF LYSINE OR LYSINE-DERIVED PRODUCTS, AND METHODS AND APPLICATIONS THEREOF CATHAY R&D CENTER CO., LTD. (CN) 2018-06-14 US disclosed
US-20170145403-A1 EXPRESSION OF POLYPEPTIDES INVOLVED IN LYSINE DECARBOXYLATION, AND METHODS AND APPLICATIONS THEREOF CATHAY R&D CENTER CO., LTD. (CN) 2017-05-25 US disclosed
US-9526231-B2 Pet chew toys of rubber and polyamide, and methods of manufacture thereof T.F.H. PUBLICATIONS, INC. (US) 2016-12-27 US disclosed
US-20160201048-A1 STABILIZED RECOMBINANT EXPRESSION PLASMID VECTOR IN HAFNIA ALVEI AND APPLICATIONS THEREOF CATHAY BIOTECH INC. (CN) 2016-07-14 US disclosed
US-9387365-B2 Golf balls having layers based on polyamide and fatty acid amide blends ACUSHNET COMPANY (US) 2016-07-12 US disclosed
US-20160128303-A1 PET CHEW TOYS OF RUBBER AND POLYAMIDE, AND METHODS OF MANUFACTURE THEREOF TRUIST BANK, AS ADMINISTRATIVE AGENT FOR THE SECURED PARTIES 2016-05-12 US disclosed
US-9234203-B2 Stabilized recombinant expression plasmid vector in hafnia alvei and applications thereof CATHAY INDUSTRIAL BIOTECH LTD. (KY) 2016-01-12 US disclosed
US-20080064831-A1 Proton-conducting polyamide polymer membrane and method for production ENERIZE CORPORATION (US) 2008-03-13 US disclosed
US-7238457-B2 Electrophotographic photoreceptor KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2007-07-03 US disclosed
US-20070148480-A1 Laminate TEIJIN LIMITED (JP) 2007-06-28 US disclosed
US-20070019984-A1 Organic photoconductor, process cartridge and image forming apparatus both employing the same KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2007-01-25 US disclosed
US-7166398-B2 Electrophotographic photoreceptor and device KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2007-01-23 US disclosed
US-20070013102-A1 Method for making polybenzobisoxazole containing fiber E. I. DU PONT DE NEMOURS AND COMPANY 2007-01-18 US disclosed
US-20070015897-A1 Method for making polybenzobisoxazole containing polymer E. I. DU PONT DE NEMOURS AND COMPANY 2007-01-18 US disclosed
US-20070015899-A1 Polybenzobisoxazole containing fiber E. I. DU PONT DE NEMOURS AND COMPANY 2007-01-18 US disclosed
US-20070015898-A1 Method for making polybenzobisoxazole containing polymer E. I. DU PONT DE NEMOURS AND COMPANY 2007-01-18 US disclosed
US-20070003853-A1 Image forming method, photoreceptor KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2007-01-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180163239-A1 EXPRESSION OF RECOMBINANT TETRACYCLINE EFFLUX PUMPS FOR THE PRODUCTION OF LYSINE OR LYSINE-DERIVED PRODUCTS, AND METHODS AND APPLICATIONS THEREOF SLC1A5, TET1, ABCB11 MGAM 1966/4885GAA 856/4885SI 1123/4885
US-11758909-B2 Antimicrobial nonwoven polyamides with zinc content PUF60, ZAP70, SLC30A7 MGAM 191/4885GAA 2811/4885SI 444/4885
US-20160201048-A1 STABILIZED RECOMBINANT EXPRESSION PLASMID VECTOR IN HAFNIA ALVEI AND APPLICATIONS THEREOF PUF60, HCFC1, TRRAP MGAM 3354/4885GAA 2901/4885SI 1188/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.