SCHEMBL14345559

SCHEMBL14345559

CNC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12

nearest known ligand 0.64

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ GHSR Q92847 7/20 0.64
▸ NLN Q9BYT8 1/20 0.64
▸ MMP1 P03956 4/20 0.55
▸ MMP9 P14780 3/20 0.55
▸ MMP8 P22894 3/20 0.55
▸ MMP3 P08254 2/20 0.55
▸ NMBR P28336 4/20 0.54
▸ MMP2 P08253 3/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12228541 1.00 GHSR (0.64) GHSRNLNMMP1MMP9MMP8
SCHEMBL21641790 0.90 NLN (0.66) GHSRNLNNMBR
SCHEMBL29479454 0.90 GHSR (0.67) GHSRNLNNMBR
SCHEMBL14279286 0.89 GHSR (0.64) GHSRNLN
SCHEMBL18862458 0.87 GHSR (0.70) GHSRNLN
SCHEMBL12202834 0.87 GHSR (0.68) GHSR
SCHEMBL21641789 0.86 NLN (0.69) GHSRNLNNMBR
SCHEMBL12202957 0.85 NLN (0.52) GHSRNLNMMP1MMP9MMP8
SCHEMBL18857368 0.85 GHSR (0.66) GHSRNLN
SCHEMBL2183813 0.84 OPRM1 (0.61) GHSRMMP1MMP9MMP8MMP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070293656-A1 COLLAGEN BINDING PEPTIDES EPIX PHARMACEUTICALS, INC. 2007-12-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070293656-A1 COLLAGEN BINDING PEPTIDES COL14A1, COL2A1, COL1A1 GHSR 2894/4885NLN 1529/4885MMP1 17/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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