Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 14/20 | 0.48 |
| ▸ | TACR1 | P25103 | 2/20 | 0.44 |
| ▸ | NTMT1 | Q9BV86 | 1/20 | 0.41 |
| ▸ | MASP2 | O00187 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13623819 | 0.95 | F2 (0.52) | F2TACR1NTMT1MASP2 | |
| SCHEMBL1432873 | 0.95 | F2 (0.52) | F2TACR1NTMT1MASP2 | |
| SCHEMBL1433336 | 0.83 | TACR1 (0.46) | F2TACR1NTMT1MASP2 | |
| SCHEMBL1431847 | 0.82 | F2 (0.50) | F2MASP2 | |
| SCHEMBL1432458 | 0.80 | F2 (0.46) | F2MASP2 | |
| SCHEMBL1432185 | 0.80 | F2 (0.46) | F2MASP2 | |
| SCHEMBL1906955 | 0.79 | NTMT1 (0.44) | TACR1NTMT1 | |
| SCHEMBL1905233 | 0.79 | NTMT1 (0.44) | TACR1NTMT1 | |
| SCHEMBL1432134 | 0.77 | F2 (0.52) | F2TACR1 | |
| SCHEMBL1433101 | 0.76 | CTSS (0.65) | F2MASP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300428-A1 | AMINOPYRIDINE DERIVATIVES | Vantia Limited (GB) | 2011-03-30 | — | — | EP | disclosed |