Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 7/20 | 0.52 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.49 |
| ▸ | CTSV | O60911 | 6/20 | 0.46 |
| ▸ | CTSL | P07711 | 6/20 | 0.46 |
| ▸ | CTSS | P25774 | 6/20 | 0.46 |
| ▸ | CTSK | P43235 | 5/20 | 0.46 |
| ▸ | CTSB | P07858 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1433599 | 0.92 | PYGL (0.50) | PYGLF2CTNNB1CTSB | |
| SCHEMBL1433165 | 0.90 | F2 (0.49) | PYGLF2CTNNB1 | |
| SCHEMBL1434012 | 0.89 | PYGL (0.52) | PYGLF2CTNNB1CTSLCTSS | |
| SCHEMBL1433255 | 0.88 | F2 (0.52) | PYGLF2CTNNB1CTSLCTSS | |
| SCHEMBL1433942 | 0.86 | CTNNB1 (0.54) | PYGLCTNNB1CTSVCTSLCTSS | |
| SCHEMBL1433349 | 0.86 | F2 (0.51) | PYGLF2CTNNB1CTSLCTSS | |
| SCHEMBL1434232 | 0.84 | F2 (0.51) | F2CTSVCTSLCTSSCTSK | |
| SCHEMBL1433514 | 0.83 | CCKBR (0.57) | CTSL | |
| SCHEMBL1433141 | 0.82 | MCHR1 (0.48) | PYGLF2CTSLCTSSCTSK | |
| SCHEMBL1433228 | 0.79 | PYGL (0.49) | PYGLCTNNB1CTSLCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300428-A1 | AMINOPYRIDINE DERIVATIVES | Vantia Limited (GB) | 2011-03-30 | — | — | EP | disclosed |