Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | QDPR | P09417 | 3/20 | 0.46 |
| ▸ | KIT | P10721 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13490356 | 0.82 | WNT3A (0.49) | ALDH1A1MAPTKDM4ETDP1MEN1 | |
| SCHEMBL14710349 | 0.80 | NAMPT (0.53) | MEN1KMT2AKITNAMPT | |
| SCHEMBL2807104 | 0.79 | ALDH1A1 (0.58) | ALDH1A1MAPTKDM4ETDP1MEN1 | |
| SCHEMBL8054238 | 0.79 | NAMPT (0.54) | ALDH1A1MAPTKDM4ENAMPTALOX15 | |
| SCHEMBL3038011 | 0.78 | ALDH1A1 (0.50) | ALDH1A1MAPTKDM4ETDP1MEN1 | |
| SCHEMBL8117386 | 0.76 | MAPT (0.43) | ALDH1A1MAPTKDM4ETDP1MEN1 | |
| SCHEMBL6214637 | 0.76 | MAPT (0.43) | ALDH1A1MAPTKDM4ETDP1MEN1 | |
| SCHEMBL7447957 | 0.76 | MAPT (0.45) | ALDH1A1MAPTKDM4ETDP1MEN1 | |
| SCHEMBL29650110 | 0.76 | LMNA (0.47) | ALDH1A1MAPTKDM4ETDP1MEN1 | |
| SCHEMBL29948559 | 0.76 | CNR1 (0.50) | ALDH1A1MAPTKDM4ETDP1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7312214-B2 | 1, 1-disubstituted cycloalkyl derivatives as factor Xa inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-12-25 | — | — | US | disclosed |