Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | BRPF1 | P55201 | 9/20 | 0.41 |
| ▸ | BRD1 | O95696 | 7/20 | 0.41 |
| ▸ | BRD4 | O60885 | 4/20 | 0.41 |
| ▸ | BRD9 | Q9H8M2 | 4/20 | 0.41 |
| ▸ | BRPF3 | Q9ULD4 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | PARG | Q86W56 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4193065 | 0.89 | TP53 (0.41) | TP53ALDH1A1BRPF1BRD1BRD4 | |
| SCHEMBL4202091 | 0.79 | ALDH1A1 (0.44) | TP53ALDH1A1BRPF1BRD1BRD4 | |
| SCHEMBL4190288 | 0.79 | ALDH1A1 (0.44) | TP53ALDH1A1BRPF1BRD1BRD4 | |
| SCHEMBL4187951 | 0.78 | ALDH1A1 (0.43) | TP53ALDH1A1BRPF1BRD1BRD4 | |
| SCHEMBL4192303 | 0.75 | BRPF1 (0.50) | ALDH1A1BRPF1BRD1BRD4BRD9 | |
| SCHEMBL4193183 | 0.75 | BRPF1 (0.50) | ALDH1A1BRPF1BRD1BRD4BRD9 | |
| SCHEMBL4193118 | 0.74 | BRPF1 (0.51) | ALDH1A1BRPF1BRD1BRD4BRD9 | |
| Cyclopentane SCHEMBL4192569 | 0.72 | KDM4E (0.48) | ALDH1A1KDM4EPKMLMNAPOLB | |
| SCHEMBL12050292 | 0.69 | BRPF1 (0.65) | TP53ALDH1A1BRPF1BRD1BRD4 | |
| Cyclopentane SCHEMBL4188224 | 0.68 | ALDH1A1 (0.44) | ALDH1A1KDM4EPKMLMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879877-B1 | ANTIMICROBIAL AGENTS | RANBAXY LAB LTD (IN) | 2013-01-02 | — | — | EP | claimed |