SCHEMBL4193183

SCHEMBL4193183

CC(CC1CCCCC1)NCc1ccccc1NS(=O)(=O)c1ccc2c(ccc(=O)n2C)c1

nearest known ligand 0.50

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
BRPF1 P55201 14/20 0.50
BRD1 O95696 9/20 0.50
BRD9 Q9H8M2 5/20 0.50
BRD4 O60885 4/20 0.50
BRPF3 Q9ULD4 6/20 0.46
ALDH1A1 P00352 1/20 0.45
KDM4E B2RXH2 1/20 0.43
PKM P14618 1/20 0.43
SCN9A Q15858 4/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4192303 1.00 BRPF1 (0.50) BRPF1BRD1BRD9BRD4BRPF3
SCHEMBL4193118 0.99 BRPF1 (0.51) BRPF1BRD1BRD9BRD4BRPF3
SCHEMBL4190288 0.90 ALDH1A1 (0.44) BRPF1BRD1BRD9BRD4ALDH1A1
SCHEMBL4202091 0.90 ALDH1A1 (0.44) BRPF1BRD1BRD9BRD4ALDH1A1
SCHEMBL4187951 0.89 ALDH1A1 (0.43) BRPF1BRD1BRD9BRD4ALDH1A1
SCHEMBL4193065 0.86 TP53 (0.41) BRPF1BRD1BRD9BRD4BRPF3
SCHEMBL4192891 0.82 POLB (0.52) ALDH1A1KDM4EPKM
SCHEMBL4186036 0.81 POLB (0.52) ALDH1A1KDM4EPKM
SCHEMBL12050344 0.81 KDM4E (0.55) ALDH1A1KDM4EPKM
SCHEMBL4192565 0.79 KDM4E (0.47) ALDH1A1KDM4EPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1879877-B1 ANTIMICROBIAL AGENTS RANBAXY LAB LTD (IN) 2013-01-02 EP claimed
US-8076370-B2 Antimicrobial agents RANBAXY LABORATORIES LIMITED (IN) 2011-12-13 US claimed
US-20090215764-A1 Antimicrobial agents RANBAXY LABORATORIES LIMITED (IN) 2009-08-27 US claimed
CN-101203504-A Antimicrobial agents RANBAXY LAB LTD (IN) 2008-06-18 CN claimed
EP-1879877-B1 ANTIMICROBIAL AGENTS RANBAXY LAB LTD (IN) 2013-01-02 EP disclosed
US-8076370-B2 Antimicrobial agents RANBAXY LABORATORIES LIMITED (IN) 2011-12-13 US disclosed
US-20090215764-A1 Antimicrobial agents RANBAXY LABORATORIES LIMITED (IN) 2009-08-27 US disclosed
CN-101203504-A Antimicrobial agents RANBAXY LAB LTD (IN) 2008-06-18 CN disclosed
EP-1879877-A2 ANTIMICROBIAL AGENTS Ranbaxy Laboratories Limited (IN) 2008-01-23 EP disclosed
WO-2006117762-A2 ANTIMICROBIAL AGENTS RANBAXY LABORATORIES LIMITED (IN) 2006-11-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090215764-A1 Antimicrobial agents TUFM, RPS17, HARS1 BRPF1 3456/4885BRD1 1986/4885BRD9 3040/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.