SCHEMBL12050292

SCHEMBL12050292

Cn1c(=O)ccc2cc(S(=O)(=O)Nc3ccccc3CO)ccc21

nearest known ligand 0.65

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
BRPF1 P55201 14/20 0.65
BRD1 O95696 10/20 0.65
BRD9 Q9H8M2 5/20 0.65
BRD4 O60885 4/20 0.65
BRPF3 Q9ULD4 6/20 0.59
PKM P14618 3/20 0.49
ALDH1A1 P00352 3/20 0.49
POLB P06746 2/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
GAA P10253 1/20 0.47
TP53 P04637 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
LMNA P02545 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13742709 0.83 BRPF1 (0.71) BRPF1BRD1BRD9BRD4BRPF3
SCHEMBL12050293 0.81 BRPF1 (0.67) BRPF1BRD1BRD9BRD4BRPF3
SCHEMBL6022235 0.80 TAS2R14 (0.47) BRPF1BRD1BRD9BRD4PKM
SCHEMBL17560706 0.80 BRPF1 (0.67) BRPF1BRD1BRD9BRD4BRPF3
SCHEMBL4193118 0.77 BRPF1 (0.51) BRPF1BRD1BRD9BRD4BRPF3
SCHEMBL4193183 0.77 BRPF1 (0.50) BRPF1BRD1BRD9BRD4BRPF3
SCHEMBL4192303 0.77 BRPF1 (0.50) BRPF1BRD1BRD9BRD4BRPF3
SCHEMBL19435605 0.74 BRPF1 (1.00) BRPF1BRD1BRD9BRD4BRPF3
SCHEMBL9329231 0.74 PTGES2 (0.51) ALDH1A1POLBLMNA
SCHEMBL31083427 0.72 LMNA (0.64) PKMALDH1A1POLBSMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8076370-B2 Antimicrobial agents RANBAXY LABORATORIES LIMITED (IN) 2011-12-13 US disclosed
US-20090215764-A1 Antimicrobial agents RANBAXY LABORATORIES LIMITED (IN) 2009-08-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090215764-A1 Antimicrobial agents TUFM, RPS17, HARS1 BRPF1 3456/4885BRD1 1986/4885BRD9 3040/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.