Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8117468 | 0.84 | MAPT (0.67) | MAPTKDM4EMAPK1 | |
| SCHEMBL10245285 | 0.82 | MAPT (0.53) | MAPTKDM4EMAPK1GAA | |
| SCHEMBL13036529 | 0.81 | SIGMAR1 (0.69) | KDM4E | |
| SCHEMBL16226139 | 0.79 | POLB (0.61) | MAPTKDM4EMAPK1 | |
| SCHEMBL13869588 | 0.79 | ALDH1A1 (0.69) | MAPTKDM4EMAPK1 | |
| SCHEMBL1507008 | 0.79 | LMNA (0.67) | MAPTKDM4E | |
| SCHEMBL18232149 | 0.79 | SIGMAR1 (0.68) | MAPK1 | |
| SCHEMBL22642436 | 0.79 | MAPT (0.61) | MAPTKDM4EMAPK1 | |
| SCHEMBL16546675 | 0.79 | MAPT (0.53) | MAPTKDM4EMAPK1 | |
| SCHEMBL24673127 | 0.78 | NCF1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291612-B2 | Immunomodulatory compounds | ACTIVE BIOTECH A.B. (SE) | 2007-11-06 | — | — | US | disclosed |
| US-7291612-B2 | Immunomodulatory compounds | ACTIVE BIOTECH A.B. (SE) | 2007-11-06 | — | — | US | disclosed |