Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | WNT3A | P56704 | 2/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.49 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | CLK1 | P49759 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22589209 | 0.89 | ALDH1A1 (0.52) | WNT3ACYP11B1CYP11B2PTPN2PTPN1 | |
| SCHEMBL14355086 | 0.86 | RAB9A (0.56) | SMN1; SMN2CYP11B1CYP11B2PTPN1ALDH1A1 | |
| SCHEMBL14355087 | 0.83 | ABL1 (0.44) | SMN1; SMN2WNT3ACYP11B1CYP11B2PTPN2 | |
| SCHEMBL4630942 | 0.79 | NOTUM (0.61) | SMN1; SMN2ALDH1A1MAPK1TDP1ALOX15 | |
| SCHEMBL14355084 | 0.77 | CYP11B1 (0.45) | SMN1; SMN2WNT3ACYP11B1CYP11B2PTPN2 | |
| SCHEMBL17465465 | 0.76 | PTPN2 (0.45) | SMN1; SMN2WNT3ACYP11B1CYP11B2PTPN2 | |
| SCHEMBL14378766 | 0.75 | PTPN1 (0.81) | SMN1; SMN2WNT3APTPN2PTPN1RAB9A | |
| SCHEMBL21012420 | 0.75 | NOTUM (0.68) | SMN1; SMN2ALDH1A1MAPK1TDP1ALOX15 | |
| SCHEMBL16200517 | 0.75 | HPGDS (0.50) | SMN1; SMN2PTPN2PTPN1ALDH1A1MAPK1 | |
| SCHEMBL1720986 | 0.74 | HSD17B10 (0.67) | SMN1; SMN2ALDH1A1MAPK1TDP1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014057874-A1 | FLUORANTHENE DERIVATIVE, LUMINESCENT ELEMENT MATERIAL CONTAINING SAME, AND LUMINESCENT ELEMENT | 東レ株式会社 (JP) | 2014-04-17 | — | — | WO | disclosed |
| US-7301029-B2 | Bipyridine Derivatives | FUJIFILM FINECHEMICALS CO., LTD. (JP) | 2007-11-27 | — | — | US | disclosed |
| US-7301029-B2 | Bipyridine Derivatives | FUJIFILM FINECHEMICALS CO., LTD. (JP) | 2007-11-27 | — | — | US | disclosed |