Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 5/20 | 0.44 |
| ▸ | BCR | P11274 | 4/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CLK1 | P49759 | 1/20 | 0.44 |
| ▸ | WNT3A | P56704 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | PRKCA | P17252 | 3/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14355085 | 0.83 | SMN1; SMN2 (0.51) | ABL1MAPTMAPK1ALDH1A1CLK1 | |
| SCHEMBL14355086 | 0.79 | RAB9A (0.56) | ABL1BCRMAPTALDH1A1CYP11B1 | |
| SCHEMBL14355084 | 0.77 | CYP11B1 (0.45) | ABL1BCRMAPTMAPK1ALDH1A1 | |
| SCHEMBL5823445 | 0.75 | RAD52 (0.48) | ABL1BCRSRCMAPTMAPK1 | |
| SCHEMBL29618407 | 0.71 | NPC1 (0.51) | ABL1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3950825 | 0.71 | NPC1 (0.51) | ABL1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL20357269 | 0.71 | CYP11B1 (0.48) | MAPTMAPK1CYP11B1CYP11B2NPC1 | |
| SCHEMBL22589209 | 0.71 | ALDH1A1 (0.52) | ABL1MAPTMAPK1ALDH1A1WNT3A | |
| SCHEMBL14378882 | 0.70 | WNT3A (0.53) | ALDH1A1WNT3APPARGPTPN2PTPN1 | |
| SCHEMBL14377943 | 0.70 | PPARG (0.54) | MAPTALDH1A1WNT3ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7301029-B2 | Bipyridine Derivatives | FUJIFILM FINECHEMICALS CO., LTD. (JP) | 2007-11-27 | — | — | US | disclosed |
| US-7301029-B2 | Bipyridine Derivatives | FUJIFILM FINECHEMICALS CO., LTD. (JP) | 2007-11-27 | — | — | US | disclosed |