Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 2/20 | 0.53 |
| ▸ | INSR | P06213 | 9/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | HTT | P42858 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.43 |
| ▸ | RAD52 | P43351 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | SNCA | P37840 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14385698 | 0.84 | ADRB2 (0.58) | ADRB2INSRADRB1MAPTHTT | |
| Bromide SCHEMBL11630617 | 0.81 | ADRB2 (0.50) | ADRB2INSRADRB1MAPTHTT | |
| Iodide SCHEMBL11631709 | 0.81 | ADRB2 (0.50) | ADRB2INSRADRB1MAPTHTT | |
| Hydrochloric Acid SCHEMBL11631456 | 0.81 | ADRB2 (0.50) | ADRB2INSRADRB1MAPTHTT | |
| SCHEMBL14386005 | 0.77 | CASP3 (0.45) | ADRB2INSRADRB1MAPTHTT | |
| SCHEMBL13208445 | 0.76 | INSR (0.51) | ADRB2INSRADRB1MAPTHTT | |
| SCHEMBL14386948 | 0.76 | INSR (0.51) | ADRB2INSRADRB1MAPTHTT | |
| SCHEMBL30846518 | 0.74 | ADRB2 (0.54) | ADRB2INSRADRB1MAPTHTT | |
| SCHEMBL16520745 | 0.74 | ADRB2 (0.54) | ADRB2INSRADRB1MAPTHTT | |
| SCHEMBL7762854 | 0.74 | ADRB2 (0.54) | ADRB2INSRADRB1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7300473-B2 | Composition for dyeing keratin fibers with a cationic direct dye and a thickening polymer | L'OREAL S.A. (FR) | 2007-11-27 | — | — | US | disclosed |
| US-20070039107-A1 | Composition for dyeing keratin fibers with a cationic direct dye and a thickening polymer | L'OREAL S.A. | 2007-02-22 | — | — | US | disclosed |