Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INSR | P06213 | 5/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 10/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | NSD2 | O96028 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 7/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14386948 | 1.00 | INSR (0.51) | INSRADRB2MAPTRAB9AHTT | |
| SCHEMBL5322756 | 0.91 | INSR (0.44) | INSRADRB2MAPTRAB9AHTT | |
| SCHEMBL5322752 | 0.91 | INSR (0.44) | INSRADRB2MAPTRAB9AHTT | |
| SCHEMBL14434747 | 0.87 | INSR (0.48) | INSRADRB2MAPTRAB9AHTT | |
| SCHEMBL16588406 | 0.86 | INSR (0.40) | INSRADRB2MAPTRAB9AHTT | |
| SCHEMBL14355663 | 0.76 | ADRB2 (0.53) | INSRADRB2MAPTRAB9AHTT | |
| SCHEMBL14182503 | 0.76 | MAPT (0.46) | MAPTRAB9APOLBMAPK1MEN1 | |
| SCHEMBL10971188 | 0.75 | INSR (0.59) | INSRADRB2MAPTRAB9AHTT | |
| SCHEMBL14385698 | 0.75 | ADRB2 (0.58) | INSRADRB2MAPTRAB9AHTT | |
| SCHEMBL10971186 | 0.75 | INSR (0.59) | INSRADRB2MAPTRAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0970685-B2 | Composition for dyeing keratinous fibres containing a cationic direct dye and a thickening polymer | ORÉAL L (FR) | 2016-10-19 | — | — | EP | disclosed |
| EP-1047388-B2 | DYEING COMPOSITION FOR KERATINOUS FIBRES WITH A DIRECT CATIONIC COLOURING AGENT AND AN ANIONIC SURFACTANT | ORÉAL L (FR) | 2015-08-19 | — | — | EP | disclosed |
| EP-0962219-B2 | Composition for the direct dying of keratinous fibres with a direct cationic dye and a polyol and/or a polyolether | OREAL (FR) | 2010-08-04 | — | — | EP | disclosed |
| EP-0971682-B2 | DYEING COMPOSITION FOR KERATIN FIBRES AND DYEING METHOD USING SAME | OREAL (FR) | 2009-09-23 | — | — | EP | disclosed |
| US-7507260-B2 | Composition for dyeing keratinous fibres with a cationic direct dye and a silicone | L'OREAL S.A. (FR) | 2009-03-24 | — | — | US | disclosed |
| US-7507260-B2 | Composition for dyeing keratinous fibres with a cationic direct dye and a silicone | L'OREAL S.A. (FR) | 2009-03-24 | — | — | US | disclosed |
| US-7485157-B2 | Dye composition for keratin fibers, with a cationic direct dye and a substantive polymer | LOREAL (FR) | 2009-02-03 | — | — | US | disclosed |
| EP-1313435-B1 | BLEACHING COMPOSITION FOR DYED KERATINOUS FIBRES | OREAL (FR) | 2008-12-03 | — | — | EP | disclosed |
| US-20080078036-A1 | Dye composition for keratin fibers, with a cationic direct dye and a substantive polymer | L'OREAL S.A. (FR) | 2008-04-03 | — | — | US | disclosed |
| EP-1432386-B1 | COSMETIC COMPOSITION CONTAINING SULPHINIC ACID DERIVATIVES | OREAL (FR) | 2008-02-27 | — | — | EP | disclosed |
| US-20070261178-A1 | Composition for dyeing keratinous fibres with a cationic direct dye and a silicone | L'OREAL S.A. | 2007-11-15 | — | — | US | disclosed |
| EP-1429714-B1 | COSMETIC COMPOSITION CONTAINING SULPHUNIC ACID DERIVATIVES | OREAL (FR) | 2007-09-26 | — | — | EP | disclosed |
| EP-1025834-B1 | Use for direct hair dye a combination of two cationic dyes | OREAL (FR) | 2007-07-04 | — | — | EP | disclosed |
| EP-1437123-B1 | COMPOSITION FOR DYEING KERATIN FIBRES AND DYEING METHOD USING SAME | OREAL (FR) | 2007-06-06 | — | — | EP | disclosed |
| US-7198652-B2 | Composition for dyeing keratinous fibers with a cationic direct dye and a quaternary ammonium salt | L'OREAL S.A. (FR) | 2007-04-03 | — | — | US | disclosed |
| US-20070039107-A1 | Composition for dyeing keratin fibers with a cationic direct dye and a thickening polymer | L'OREAL S.A. | 2007-02-22 | — | — | US | disclosed |
| US-7179300-B2 | Cosmetic composition containing sulfinic acid derivatives | L'OREAL S.A. (FR) | 2007-02-20 | — | — | US | disclosed |
| US-7179300-B2 | Cosmetic composition containing sulfinic acid derivatives | L'OREAL S.A. (FR) | 2007-02-20 | — | — | US | disclosed |
| US-20070006396-A9 | Composition for dyeing keratin fibers with a cationic direct dye and a thickening polymer | L'OREAL S.A. | 2007-01-11 | — | — | US | disclosed |
| US-20070006396-A9 | Composition for dyeing keratin fibers with a cationic direct dye and a thickening polymer | L'OREAL S.A. | 2007-01-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080078036-A1 | Dye composition for keratin fibers, with a cationic direct dye and a substantive polymer | KRT18, DSG1, KRTCAP2 | INSR 4703/4885ADRB2 4788/4885MAPT 469/4885 |
| US-20070006396-A9 | Composition for dyeing keratin fibers with a cationic direct dye and a thickening polymer | KRT18, HKDC1, DSG1 | INSR 1597/4885ADRB2 4606/4885MAPT 177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.