Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 3/20 | 0.46 |
| ▸ | DRD3 | P35462 | 3/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | BRPF1 | P55201 | 3/20 | 0.42 |
| ▸ | BRD9 | Q9H8M2 | 3/20 | 0.42 |
| ▸ | BRD4 | O60885 | 2/20 | 0.42 |
| ▸ | HTR6 | P50406 | 2/20 | 0.42 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.39 |
| ▸ | HTR3B | O95264 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.39 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14356008 | 0.87 | HTR1A (0.50) | NCF1DRD2DRD3HTR1ADRD4 | |
| SCHEMBL5343839 | 0.79 | ACHE (0.48) | — | |
| SCHEMBL14355884 | 0.79 | DRD2 (0.54) | DRD2DRD3HTR1ADRD4HTR2A | |
| SCHEMBL14355879 | 0.78 | NCF1 (0.50) | NCF1DRD2DRD3HTR1ADRD4 | |
| SCHEMBL14355865 | 0.78 | BRD9 (0.44) | ADRA2CBRPF1BRD9BRD4BRD7 | |
| SCHEMBL14355815 | 0.78 | DRD2 (0.51) | NCF1DRD2DRD3HTR1ADRD4 | |
| SCHEMBL14355878 | 0.77 | NCF1 (0.49) | NCF1DRD2DRD3HTR1ADRD4 | |
| Sifaprazine SCHEMBL21524898 | 0.76 | NCF1 (0.58) | NCF1DRD2DRD3HTR1ADRD4 | |
| SCHEMBL14355806 | 0.76 | MC4R (0.50) | NCF1DRD2DRD3HTR1ADRD4 | |
| SCHEMBL8361520 | 0.76 | DRD2 (0.72) | NCF1DRD2DRD3HTR1ADRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291619-B2 | Melanocortin receptor agonists | ELI LILLY AND COMPANY (US) | 2007-11-06 | — | — | US | disclosed |