Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | CETP | P11597 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13236095 | 0.89 | MEN1 (0.53) | MAPTALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL14387674 | 0.87 | ALDH1A1 (0.46) | MAPTALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL28674555 | 0.79 | RAB9A (0.59) | MAPTALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL30343191 | 0.78 | CETP (0.44) | MAPTALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL28346162 | 0.75 | CETP (0.54) | MAPTALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL11218848 | 0.73 | ALDH1A1 (0.63) | MAPTALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL6718812 | 0.70 | ALDH1A1 (0.59) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL28693497 | 0.70 | CETP (0.48) | MAPTALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL28674605 | 0.69 | FFAR1 (0.51) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL30343194 | 0.68 | KMT2A (0.42) | ALDH1A1L3MBTL1MEN1KMT2ACETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7297820-B2 | Stilbene derivatives and their use for binding and imaging amyloid plaques | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2007-11-20 | — | — | US | disclosed |