Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 5/20 | 0.47 |
| ▸ | HTR1A | P08908 | 4/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MLNR | O43193 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | HTR5A | P47898 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14355991 | 0.87 | HTR1A (0.50) | HTR6HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL14355990 | 0.82 | HTR1A (0.49) | HTR6HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5335774 | 0.79 | ACHE (0.47) | CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL14355996 | 0.79 | HTR1A (0.46) | HTR6HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8447358 | 0.78 | HTR6 (0.47) | HTR6HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL14355988 | 0.78 | HTR1A (0.47) | HTR6HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6222309 | 0.76 | HTR1A (0.54) | HTR6HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4520348 | 0.75 | HTR1A (0.55) | HTR6HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL31561598 | 0.74 | HTR1A (0.73) | HTR6HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL335802 | 0.74 | HTR1A (0.73) | HTR6HTR1ASLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291619-B2 | Melanocortin receptor agonists | ELI LILLY AND COMPANY (US) | 2007-11-06 | — | — | US | disclosed |