Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | USP2 | O75604 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5358313 | 0.80 | PAX8 (0.40) | SMN1; SMN2GAATSHRUSP2RECQL | |
| SCHEMBL5726545 | 0.76 | ALDH1A1 (0.40) | SMN1; SMN2GAATSHRUSP2RECQL | |
| SCHEMBL5764788 | 0.74 | PAX8 (0.40) | GAAALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL14356237 | 0.74 | BRS3 (0.47) | SMN1; SMN2GAATSHRUSP2RECQL | |
| SCHEMBL14356238 | 0.72 | SMN1; SMN2 (0.41) | SMN1; SMN2GAATSHRUSP2RECQL | |
| SCHEMBL14356278 | 0.72 | CXCL8 (0.44) | SMN1; SMN2GAATSHRUSP2ALDH1A1 | |
| SCHEMBL5370928 | 0.71 | ALDH1A1 (0.41) | SMN1; SMN2TSHRUSP2ALDH1A1NPSR1 | |
| SCHEMBL5377800 | 0.70 | TSHR (0.42) | GAATSHRALDH1A1KMT2A | |
| SCHEMBL6511360 | 0.70 | TDP1 (0.43) | GAATSHRALDH1A1L3MBTL1 | |
| SCHEMBL14356225 | 0.70 | MAPK1 (0.39) | SMN1; SMN2GAATSHRUSP2RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7294716-B2 | Process for preparing isomerically pure prodrugs of proton pump inhibitors | ALLERGAN, INC. (US) | 2007-11-13 | — | — | US | disclosed |