Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYTH2 | Q99418 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.36 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5377800 | 0.84 | TSHR (0.42) | ALDH1A1TSHRLMNAHTTTDP1 | |
| SCHEMBL14356225 | 0.83 | MAPK1 (0.39) | ALDH1A1TSHRLMNAHTTTDP1 | |
| SCHEMBL6511360 | 0.83 | TDP1 (0.43) | ALDH1A1TSHRLMNAHTTTDP1 | |
| SCHEMBL14356239 | 0.76 | SMN1; SMN2 (0.49) | ALDH1A1TSHRSMN1; SMN2USP2GAA | |
| SCHEMBL14356278 | 0.73 | CXCL8 (0.44) | ALDH1A1TSHRLMNAHTTTDP1 | |
| SCHEMBL5378083 | 0.73 | RORC (0.35) | ALDH1A1TSHRLMNAHTTGAA | |
| SCHEMBL14387883 | 0.73 | MAPK1 (0.48) | ALDH1A1TSHRLMNASMN1; SMN2GAA | |
| SCHEMBL5359147 | 0.73 | CXCL8 (0.44) | ALDH1A1TSHRLMNAHTTSMN1; SMN2 | |
| SCHEMBL5370928 | 0.70 | ALDH1A1 (0.41) | ALDH1A1TSHRLMNAHTTSMN1; SMN2 | |
| SCHEMBL5370451 | 0.70 | CXCL8 (0.39) | ALDH1A1TSHRLMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1556371-B1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS PRODRUGS OF PROTON PUMP INHIBITOR | WINSTON PHARMACEUTICALS LLC (US) | 2006-04-19 | — | — | EP | disclosed |
| EP-1644352-A1 | PROCESS FOR PREPARING ISOMERICALLY PURE PRODRUGS OF PROTON PUMP INHIBITORS | Allergan, Inc. (US) | 2006-04-12 | — | — | EP | disclosed |
| WO-2005016917-A1 | PROCESS FOR PREPARING ISOMERICALLY PURE PRODRUGS OF PROTON PUMP INHIBITORS | ALLERGAN, INC. (US) | 2005-02-24 | — | — | WO | disclosed |