SCHEMBL1435786

SCHEMBL1435786

O=C/C=C/c1ccc(F)cc1

nearest known ligand 0.60

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.60
KDM4E B2RXH2 1/20 0.60
MAPT P10636 1/20 0.60
TRPA1 O75762 1/20 0.58
LMNA P02545 1/20 0.58
ALOX5 P09917 1/20 0.58
MAPK1 P28482 1/20 0.58
NFE2L2 Q16236 7/20 0.52
HSD11B1 P28845 1/20 0.52
FBP1 P09467 1/20 0.48
XDH P47989 1/20 0.48
TNFRSF1A P19438 1/20 0.47
APP P05067 1/20 0.45
PTGS1 P23219 1/20 0.45
TXNRD1 Q16881 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1435787 1.00 ALDH1A1 (0.60) ALDH1A1KDM4EMAPTTRPA1LMNA
SCHEMBL5725736 0.93 ALDH1A1 (0.54) ALDH1A1KDM4EMAPTTRPA1LMNA
SCHEMBL2558472 0.91 ALDH1A1 (0.50) ALDH1A1KDM4EMAPTTRPA1LMNA
SCHEMBL2558475 0.91 ALDH1A1 (0.50) ALDH1A1KDM4EMAPTTRPA1LMNA
SCHEMBL1310214 0.87 ALDH1A1 (0.75) ALDH1A1KDM4EMAPTTRPA1LMNA
SCHEMBL1310216 0.87 ALDH1A1 (0.75) ALDH1A1KDM4EMAPTTRPA1LMNA
Cinnamaldehyde SCHEMBL28939820 0.84 ALDH1A1 (0.78) ALDH1A1KDM4EMAPTTRPA1LMNA
SCHEMBL9970459 0.84 NFE2L2 (0.62) NFE2L2HSD11B1FBP1TNFRSF1AAPP
SCHEMBL1308775 0.79 ALDH1A1 (0.65) ALDH1A1KDM4EMAPTTRPA1LMNA
SCHEMBL1308773 0.79 ALDH1A1 (0.65) ALDH1A1KDM4EMAPTTRPA1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 254 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12234384-B2 Adhesion-improving composition for textile material and associated reinforcing textile material PORCHER INDUSTRIES (FR) 2025-02-25 US claimed
CN-119456012-A N-doped modified MOFs (metal-organic frameworks) derived core-shell nano-reactor, and preparation method and application thereof 湖北汽车工业学院 2025-02-18 CN claimed
CN-118859629-A Water-soluble photosensitive composite dry film and preparation method thereof 广东泰亚达光电有限公司 2024-10-29 CN claimed
CN-118852032-A Alpha, beta-unsaturated ketone derivative, preparation method and application thereof 赣南医科大学 2024-10-29 CN claimed
CN-118164998-A Sesquiterpene lactone scaberol C dithio carbamate derivative and preparation method and application thereof 沈阳药科大学 2024-06-11 CN claimed
CN-118164996-A Sesquiterpene lactone scaberol C selenoether derivative, preparation method and application thereof 沈阳药科大学 2024-06-11 CN claimed
CN-118164997-A Sesquiterpene lactone scaberol C thioether derivative, and preparation method and application thereof 沈阳药科大学 2024-06-11 CN claimed
CN-112135862-B Composition for improving the adhesion of textile materials and related reinforced textile materials 博舍工业公司 2022-06-03 CN claimed
WO-2021259288-A1 AGONIST OF DEACETYLASE AND USE THEREOF 广州中医药大学(广州中医药研究院) 2021-12-30 WO claimed
CN-111153910-B Elephantopus scaber seed lactone derivative and preparation method and application thereof 沈阳药科大学 2021-07-30 CN claimed
US-20210115310-A1 ADHESION-IMPROVING COMPOSITION FOR TEXTILE MATERIAL AND ASSOCIATED REINFORCING TEXTILE MATERIAL PORCHER INDUSTRIES (FR) 2021-04-22 US claimed
EP-3784719-A1 ADHERENCE-IMPROVING COMPOSITION FOR TEXTILE MATERIAL AND ASSOCIATED REINFORCING TEXTILE MATERIAL Porcher Industries (FR) 2021-03-03 EP claimed
CN-112135862-A Composition for improving the adhesion of textile materials and related reinforced textile materials 博舍工业公司 2020-12-25 CN claimed
CN-111153910-A Elephantopus scaber seed lactone derivative and preparation method and application thereof 沈阳药科大学 2020-05-15 CN claimed
CN-110563936-A Self-flame-retardant antibacterial water-based polyester resin and preparation method thereof 合众(佛山)化工有限公司 2019-12-13 CN claimed
US-20090022729-A1 METHODS AND COMPOSITIONS FOR TREATING CARDIAC DYSFUNCTIONS NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR 2009-01-22 US claimed
EP-1963344-A1 ORGANOPHOSPHORIC DERIVATIVES USEFUL AS ANTI-PARASITIC AGENTS UNIVERSITEIT GENT (BE) 2008-09-03 EP claimed
WO-2007071453-A1 ORGANOPHOSPHORIC DERIVATIVES USEFUL AS ANTI-PARASITIC AGENTS UNIVERSITEIT GENT (BE) 2007-06-28 WO claimed
CN-120682125-B 1-Hydroxy-1-sodium sulfonate structural compound based on cinnamaldehyde derivative, and preparation method and application thereof 中国农业大学 2026-05-15 CN disclosed
US-4012377-A ANTIMICROBIAL, PARASITICIDES GLAXO LABORATORIES LIMITED (EN) 1977-03-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090022729-A1 METHODS AND COMPOSITIONS FOR TREATING CARDIAC DYSFUNCTIONS TNNI3, MYLK2, FABP3 ALDH1A1 2037/4885KDM4E 4135/4885MAPT 4643/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.