SCHEMBL1435787

SCHEMBL1435787

O=CC=Cc1ccc(F)cc1

nearest known ligand 0.60

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.60
KDM4E B2RXH2 1/20 0.60
MAPT P10636 1/20 0.60
TRPA1 O75762 1/20 0.58
LMNA P02545 1/20 0.58
ALOX5 P09917 1/20 0.58
MAPK1 P28482 1/20 0.58
NFE2L2 Q16236 7/20 0.52
HSD11B1 P28845 1/20 0.52
FBP1 P09467 1/20 0.48
XDH P47989 1/20 0.48
TNFRSF1A P19438 1/20 0.47
APP P05067 1/20 0.45
PTGS1 P23219 1/20 0.45
TXNRD1 Q16881 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1435786 1.00 ALDH1A1 (0.60) ALDH1A1KDM4EMAPTTRPA1LMNA
SCHEMBL5725736 0.93 ALDH1A1 (0.54) ALDH1A1KDM4EMAPTTRPA1LMNA
SCHEMBL2558472 0.91 ALDH1A1 (0.50) ALDH1A1KDM4EMAPTTRPA1LMNA
SCHEMBL2558475 0.91 ALDH1A1 (0.50) ALDH1A1KDM4EMAPTTRPA1LMNA
SCHEMBL1310214 0.87 ALDH1A1 (0.75) ALDH1A1KDM4EMAPTTRPA1LMNA
SCHEMBL1310216 0.87 ALDH1A1 (0.75) ALDH1A1KDM4EMAPTTRPA1LMNA
Cinnamaldehyde SCHEMBL28939820 0.84 ALDH1A1 (0.78) ALDH1A1KDM4EMAPTTRPA1LMNA
SCHEMBL9970459 0.84 NFE2L2 (0.62) NFE2L2HSD11B1FBP1TNFRSF1AAPP
SCHEMBL1308775 0.79 ALDH1A1 (0.65) ALDH1A1KDM4EMAPTTRPA1LMNA
SCHEMBL1308773 0.79 ALDH1A1 (0.65) ALDH1A1KDM4EMAPTTRPA1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 181 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12234384-B2 Adhesion-improving composition for textile material and associated reinforcing textile material PORCHER INDUSTRIES (FR) 2025-02-25 US claimed
CN-119456012-A N-doped modified MOFs (metal-organic frameworks) derived core-shell nano-reactor, and preparation method and application thereof 湖北汽车工业学院 2025-02-18 CN claimed
CN-118852032-A Alpha, beta-unsaturated ketone derivative, preparation method and application thereof 赣南医科大学 2024-10-29 CN claimed
CN-118859629-A Water-soluble photosensitive composite dry film and preparation method thereof 广东泰亚达光电有限公司 2024-10-29 CN claimed
CN-112826812-B Pharmaceutical composition for treating colon cancer and application thereof 青岛大学 2023-08-25 CN claimed
CN-112694392-B TRPV3 inhibitor and preparation method thereof 青岛大学 2022-11-22 CN claimed
CN-112135862-B Composition for improving the adhesion of textile materials and related reinforced textile materials 博舍工业公司 2022-06-03 CN claimed
WO-2021259288-A1 AGONIST OF DEACETYLASE AND USE THEREOF 广州中医药大学(广州中医药研究院) 2021-12-30 WO claimed
CN-112826812-A Pharmaceutical composition for treating colon cancer and application thereof 青岛大学 2021-05-25 CN claimed
US-20210115310-A1 ADHESION-IMPROVING COMPOSITION FOR TEXTILE MATERIAL AND ASSOCIATED REINFORCING TEXTILE MATERIAL PORCHER INDUSTRIES (FR) 2021-04-22 US claimed
EP-3784719-A1 ADHERENCE-IMPROVING COMPOSITION FOR TEXTILE MATERIAL AND ASSOCIATED REINFORCING TEXTILE MATERIAL Porcher Industries (FR) 2021-03-03 EP claimed
CN-112135862-A Composition for improving the adhesion of textile materials and related reinforced textile materials 博舍工业公司 2020-12-25 CN claimed
US-10800790-B2 Sesquiterpenoid STAT3 inhibitors UNIVERSITY OF HAWAII (US) 2020-10-13 US claimed
CN-109627492-B Preparation method and application of antibacterial hydrophobic inorganic-organic hybrid antibacterial agent 浙江工业大学 2020-08-18 CN claimed
CN-110563936-A Self-flame-retardant antibacterial water-based polyester resin and preparation method thereof 合众(佛山)化工有限公司 2019-12-13 CN claimed
US-20160137663-A1 NOVEL SESQUITERPENOID STAT3 INHIBITORS UNIVERSITY OF HAWAII (US) 2016-05-19 US claimed
WO-2014205416-A1 NOVEL SESQUITERPENOID STAT3 INHIBITORS UNIVERSITY OF HAWAII (US) 2014-12-24 WO claimed
EP-1963344-A1 ORGANOPHOSPHORIC DERIVATIVES USEFUL AS ANTI-PARASITIC AGENTS UNIVERSITEIT GENT (BE) 2008-09-03 EP claimed
WO-2007071453-A1 ORGANOPHOSPHORIC DERIVATIVES USEFUL AS ANTI-PARASITIC AGENTS UNIVERSITEIT GENT (BE) 2007-06-28 WO claimed
CN-119859122-B Tyrosinase inhibitor and preparation method and application thereof 杭州师范大学 2025-06-13 CN disclosed
CN-119386930-B Noble metal-Ni coexisting supported catalyst prepared based on Ni-MOF metal node partial reduction, preparation method and application 浙江师范大学 2025-05-30 CN disclosed
CN-120004889-A ALK5 kinase inhibitor and preparation method and application thereof 延边大学 2025-05-16 CN disclosed
CN-119859122-A Tyrosinase inhibitor and preparation method and application thereof 杭州师范大学 2025-04-22 CN disclosed
WO-2025053103-A1 RESIN COMPOSITION EXCELLENT IN TRANSPARENCY AND MOLDED ARTICLE THEREOF 株式会社ヘミセルロース 2025-03-13 WO disclosed
US-12234384-B2 Adhesion-improving composition for textile material and associated reinforcing textile material PORCHER INDUSTRIES (FR) 2025-02-25 US disclosed
CN-119456012-A N-doped modified MOFs (metal-organic frameworks) derived core-shell nano-reactor, and preparation method and application thereof 湖北汽车工业学院 2025-02-18 CN disclosed
CN-119386930-A Noble metal-Ni coexisting supported catalyst prepared based on Ni-MOF metal node partial reduction, preparation method and application 浙江师范大学 2025-02-07 CN disclosed
US-20250034121-A1 COMPOUNDS AND THEIR USES AS GPR183 INHIBITORS NANJING IMMUNOPHAGE BIOMEDICAL CO., LTD. (CN) 2025-01-30 US disclosed
CN-118859629-B Water-soluble photosensitive composite dry film and preparation method thereof 广东泰亚达光电有限公司 2024-12-20 CN disclosed
CN-115151550-B External nucleotide pyrophosphatase/phosphodiesterase 1 (ENPP 1) modulators and uses thereof 桑福德·伯纳姆·普雷比医学发现研究所 2024-11-22 CN disclosed
CN-118930392-A Aldehyde deoxidization and reduction method 温州医科大学 2024-11-12 CN disclosed
CN-118852032-A Alpha, beta-unsaturated ketone derivative, preparation method and application thereof 赣南医科大学 2024-10-29 CN disclosed
CN-118859629-A Water-soluble photosensitive composite dry film and preparation method thereof 广东泰亚达光电有限公司 2024-10-29 CN disclosed
US-12043602-B2 Fendiline derivatives THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2024-07-23 US disclosed
US-20240228797-A1 LIQUID REPELLENT SLIPPERY SURFACES AND METHODS OF PREPARATION THEREOF UNIVERSITY OF DURHAM (GB) 2024-07-11 US disclosed
CN-114058369-B Fluorescent probe based on styryl oxazolone compound and biological application thereof 中国科学院上海药物研究所 2024-07-02 CN disclosed
CN-117945820-A Method for synthesizing alpha, beta-unsaturated aldehyde compound by copper catalysis 江苏海洋大学 2024-04-30 CN disclosed
EP-4326071-A1 LIQUID REPELLENT SLIPPERY SURFACES AND METHODS OF PREPARATION THEREOF University Of Durham (GB) 2024-02-28 EP disclosed
CN-117430651-A Nucleoside monophosphate compound and preparation method thereof 武汉精准智药科技有限公司 2024-01-23 CN disclosed
US-11851433-B2 Compounds, compositions and methods DENALI THERAPEUTICS INC. (US) 2023-12-26 US disclosed
CN-116789594-A Synthesis method of N-alkylated pyridine-2-ketone derivative 常州大学 2023-09-22 CN disclosed
EP-3625234-B1 HEXAHYDROPYRAZOLO [1,2-A] DIAZEPINONES AND RELATED HETEROCYCLES AS INHIBITORS OF RIP-1 KINASE DENALI THERAPEUTICS INC (US) 2023-09-20 EP disclosed
US-20230279246-A1 MOLECULE-CONTAINING SURFACES AND METHODS OF PREPARATION THEREOF UNIVERSITY OF DURHAM (GB) 2023-09-07 US disclosed
CN-112826812-B Pharmaceutical composition for treating colon cancer and application thereof 青岛大学 2023-08-25 CN disclosed
EP-4192244-A1 MOLECULE-CONTAINING SURFACES AND METHODS OF PREPARATION THEREOF University of Durham (GB) 2023-06-14 EP disclosed
CN-114436767-B Method for preparing alcohol compound based on zinc acetate catalytic carbonyl reduction 延安大学 2023-05-26 CN disclosed
US-20230121698-A1 ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE 1 (ENPP1) MODULATORS AND USES THEREOF Sanford Burnham Prebys Medical Discovery Institute 2023-04-20 US disclosed
WO-2022248877-A1 LIQUID REPELLENT SLIPPERY SURFACES AND METHODS OF PREPARATION THEREOF UNIVERSITY OF DURHAM (GB) 2022-12-01 WO disclosed
CN-112694392-B TRPV3 inhibitor and preparation method thereof 青岛大学 2022-11-22 CN disclosed
EP-4081528-A1 ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE 1 (ENPP1) MODULATORS AND USES THEREOF Sanford Burnham Prebys Medical Discovery Institute (US) 2022-11-02 EP disclosed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
CN-115151550-A Ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP 1) modulators and uses thereof 桑福德·伯纳姆·普雷比医学发现研究所 2022-10-04 CN disclosed
US-20220177440-A1 Fendiline Derivatives THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM 2022-06-09 US disclosed
CN-112135862-B Composition for improving the adhesion of textile materials and related reinforced textile materials 博舍工业公司 2022-06-03 CN disclosed
CN-114436767-A Method for preparing alcohol compound based on carbonyl reduction catalyzed by zinc acetate 延安大学 2022-05-06 CN disclosed
CN-109851570-B Chalcone derivative containing 1,2, 4-triazine, preparation method and application thereof 贵州大学 2022-04-19 CN disclosed
CN-110002952-B Preparation method of alpha, beta-unsaturated alcohol and/or alpha, beta-saturated alcohol 赣南医学院 2022-03-15 CN disclosed
CN-114058369-A Fluorescent probe based on styrene oxazolone compound and biological application thereof 中国科学院上海药物研究所 2022-02-18 CN disclosed
WO-2022029432-A1 MOLECULE-CONTAINING SURFACES AND METHODS OF PREPARATION THEREOF UNIVERSITY OF DURHAM (GB) 2022-02-10 WO disclosed
US-20220024938-A1 Compounds, Compositions and Methods DENALI THERAPEUTICS INC. (US) 2022-01-27 US disclosed
WO-2021259288-A1 AGONIST OF DEACETYLASE AND USE THEREOF 广州中医药大学(广州中医药研究院) 2021-12-30 WO disclosed
US-11174262-B2 Compounds, compositions and methods DENALI THERAPEUTICS INC. (US) 2021-11-16 US disclosed
CN-113384566-A Application of cinnamaldehyde and derivatives thereof as histone deacetylase agonists 广州中医药大学(广州中医药研究院) 2021-09-14 CN disclosed
CN-107827852-B Patchoulenone derivative and preparation method and application thereof 成都中医药大学 2021-08-20 CN disclosed
CN-113135816-A Method for synthesizing photoactive bromohydrin compound 常州大学 2021-07-20 CN disclosed
WO-2021133915-A1 ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE 1 (ENPP1) MODULATORS AND USES THEREOF Sanford Burnham Prebys Medical Discovery Institute (US) 2021-07-01 WO disclosed
CN-112826812-A Pharmaceutical composition for treating colon cancer and application thereof 青岛大学 2021-05-25 CN disclosed
CN-112694392-A TRPV3 inhibitor and preparation method thereof 青岛大学 2021-04-23 CN disclosed
US-20210115310-A1 ADHESION-IMPROVING COMPOSITION FOR TEXTILE MATERIAL AND ASSOCIATED REINFORCING TEXTILE MATERIAL PORCHER INDUSTRIES (FR) 2021-04-22 US disclosed
US-20210070756-A1 TETRACYCLIC BROMODOMAIN INHIBITORS ABBVIE INC (US) 2021-03-11 US disclosed
CN-108558851-B Coumarin-oxazole-ethylene type alpha-glucosidase inhibitor and preparation method and application thereof 贵州医科大学 2021-03-05 CN disclosed
EP-3784719-A1 ADHERENCE-IMPROVING COMPOSITION FOR TEXTILE MATERIAL AND ASSOCIATED REINFORCING TEXTILE MATERIAL Porcher Industries (FR) 2021-03-03 EP disclosed
CN-110746253-B Synthesis method of beta, beta-disubstituted propionate derivative 南京工业大学 2021-02-05 CN disclosed
CN-112135862-A Composition for improving the adhesion of textile materials and related reinforced textile materials 博舍工业公司 2020-12-25 CN disclosed
CN-111840261-A Deacetylase agonist and application thereof 广州中医药大学(广州中医药研究院) 2020-10-30 CN disclosed
CN-111840261-A Deacetylase agonist and application thereof 广州中医药大学(广州中医药研究院) 2020-10-30 CN disclosed
US-10800790-B2 Sesquiterpenoid STAT3 inhibitors UNIVERSITY OF HAWAII (US) 2020-10-13 US disclosed
EP-3164386-B1 PIPERIDINONE HERBICIDES FMC CORP (US) 2020-10-07 EP disclosed
US-20200291027-A1 TETRACYCLIC BROMODOMAIN INHIBITORS ABBVIE INC (US) 2020-09-17 US disclosed
CN-110002987-B Phenylallylidene cyclohexenone derivative, preparation method and application thereof 南通大学 2020-09-15 CN disclosed
EP-3313837-B1 CARBOLINE ANTIPARASITICS ZOETIS SERVICES LLC (US) 2020-09-09 EP disclosed
CN-109627492-B Preparation method and application of antibacterial hydrophobic inorganic-organic hybrid antibacterial agent 浙江工业大学 2020-08-18 CN disclosed
CN-111499657-A Synthetic method of isoquinoline oxazolidine 蚌埠学院 2020-08-07 CN disclosed
US-10709692-B2 Isoxazolidine derived inhibitors of receptor interacting protein kinase 1 (RIPK1) DENALI THERAPEUTICS INC. (US) 2020-07-14 US disclosed
CN-107778256-B Method for synthesizing quinazolinone from anthranilamide and unsaturated aldehyde 南京理工大学 2020-06-19 CN disclosed
EP-3625234-A1 COMPOUNDS, COMPOSITIONS AND METHODS Denali Therapeutics Inc. (US) 2020-03-25 EP disclosed
CN-110914275-A Compounds, compositions and methods 戴纳立制药公司 2020-03-24 CN disclosed
US-20200079784-A1 Compounds, Compositions and Methods DENALI THERAPEUTICS INC. (US) 2020-03-12 US disclosed
US-10570129-B2 Carboline antiparasitics ZOETIS SERVICES LLC (US) 2020-02-25 US disclosed
CN-110746253-A Synthesis method of β -disubstituted propionate derivative 南京工业大学 2020-02-04 CN disclosed
WO-2020021735-A1 RESIN-COATED METALLIC PIGMENT DIC株式会社 2020-01-30 WO disclosed
US-20200031822-A1 CARBOLINE ANTIPARASITICS ZOETIS SERVICES LLC (US) 2020-01-30 US disclosed
CN-110563936-A Self-flame-retardant antibacterial water-based polyester resin and preparation method thereof 合众(佛山)化工有限公司 2019-12-13 CN disclosed
US-20190337956-A1 NEUROACTIVE COMPOUNDS AND METHODS OF USING SAME The General Hospita Corporation (US) 2019-11-07 US disclosed
US-20190315691-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF PAROXETINE AND ITS INTERMEDIATE Piramal Enterprises Limited (IN) 2019-10-17 US disclosed
EP-3539962-A1 TETRACYCLIC BROMODOMAIN INHIBITORS AbbVie Inc. (US) 2019-09-18 EP disclosed
US-10301318-B2 Neuroactive compounds and methods of using the same THE GENERAL HOSPITAL CORPORATION (US) 2019-05-28 US disclosed
EP-2970330-B1 TETRACYCLIC BROMODOMAIN INHIBITORS ABBVIE INC (US) 2019-04-17 EP disclosed
US-20180353480-A1 ISOXAZOLIDINE DERIVED INHIBITORS OF RECEPTOR INTERACTING PROTEIN KINASE 1 (RIPK1) APTUIT (VERONA) S.R.L. (IT) 2018-12-13 US disclosed
WO-2018213634-A1 COMPOUNDS, COMPOSITIONS AND METHODS DENALI THERAPEUTICS INC. (US) 2018-11-22 WO disclosed
US-20180298003-A1 TETRACYCLIC BROMODOMAIN INHIBITORS ABBVIE INC (US) 2018-10-18 US disclosed
US-10035800-B2 Substituted 1,4,10-triazadibenzo[cd,f]azulenes, substituted 1,4,5,10-tetraazadibenzo[cd,f]azulenes and substituted 1,4,5,7,10-pentaazadibenzo[cd,f]azulenes as bromodomain inhibitors ABBVIE INC. (US) 2018-07-31 US disclosed
EP-3344602-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF PAROXETINE AND ITS INTERMEDIATE Piramal Enterprises Limited (IN) 2018-07-11 EP disclosed
EP-3313837-A1 CARBOLINE ANTIPARASITICS Zoetis Services LLC (US) 2018-05-02 EP disclosed
US-9944602-B2 Piperidinone herbicides FMC CORPORATION 2018-04-17 US disclosed
US-9776979-B2 EBI2 modulators SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) 2017-10-03 US disclosed
US-9758480-B2 1-(cycloalkyl-carbonyl)proline derivative SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) 2017-09-12 US disclosed
US-20170247383-A1 NEUROACTIVE COMPOUNDS AND METHODS OF USING THE SAME THE GENERAL HOSPITAL CORPORATION (US) 2017-08-31 US disclosed
US-9718840-B2 Condensed 5-oxazolidinone derivative SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) 2017-08-01 US disclosed
WO-2017096301-A1 ISOXAZOLIDINE DERIVED INHIBITORS OF RECEPTOR INTERACTING PROTEIN KINASE 1 (RIPK 1) DENALI THERAPEUTICS INC. (US) 2017-06-08 WO disclosed
US-20170158638-A1 PIPERIDINONE HERBICIDES FMC CORPORATION 2017-06-08 US disclosed
EP-3164386-A1 PIPERIDINONE HERBICIDES E. I. du Pont de Nemours and Company (US) 2017-05-10 EP disclosed
WO-2017037662-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF PAROXETINE AND ITS INTERMEDIATE Piramal Enterprises Limited (IN) 2017-03-09 WO disclosed
US-20170022218-A1 CONDENSED 5-OXAZOLIDINONE DERIVATIVE SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) 2017-01-26 US disclosed
WO-2016209635-A1 CARBOLINE ANTIPARASITICS ZOETIS SERVICES LLC (US) 2016-12-29 WO disclosed
EP-3095786-A1 CONDENSED 5-OXAZOLIDINONE DERIVATIVE Sumitomo Dainippon Pharma Co., Ltd. (JP) 2016-11-23 EP disclosed
EP-3087072-A2 SPIROINDOLINE ANTIPARASITIC DERIVATIVES Zoetis Services LLC (US) 2016-11-02 EP disclosed
US-20160296499-A1 Spiroindoline Antiparasitic Derivatives ZOETIS SERVICES LLC 2016-10-13 US disclosed
US-20160214951-A1 EBI2 MODULATORS SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE 2016-07-28 US disclosed
CN-105777970-A Preparation method of adsorbent for refining trimesic acid 张玲 2016-07-20 CN disclosed
US-20160137663-A1 NOVEL SESQUITERPENOID STAT3 INHIBITORS UNIVERSITY OF HAWAII (US) 2016-05-19 US disclosed
US-9290427-B2 Anti-invasive compounds UNIVERSITEIT GENT (BE) 2016-03-22 US disclosed
WO-2016003997-A1 PIPERIDINONE HERBICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2016-01-07 WO disclosed
WO-2015200674-A1 NEUROACTIVE COMPOUNDS AND METHODS OF USING THE SAME THE GENERAL HOSPITAL CORPORATION (US) 2015-12-30 WO disclosed
US-20150210640-A1 1-(CYCLOALKYL-CARBONYL)PROLINE DERIVATIVE SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) 2015-07-30 US disclosed
WO-2015100232-A2 SPIROINDOLINE ANTIPARASITIC DERIVATIVES ZOETIS SERVICES LLC (US) 2015-07-02 WO disclosed
EP-2876105-A1 1-(CYCLOALKYL-CARBONYL)PROLINE DERIVATIVE Sumitomo Dainippon Pharma Co., Ltd. (JP) 2015-05-27 EP disclosed
WO-2015048570-A2 EBI2 MODULATORS SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) 2015-04-02 WO disclosed
US-20150011620-A1 ANTI-INVASIVE COMPOUNDS UNIVERSITEIT GENT (BE) 2015-01-08 US disclosed
WO-2014205416-A1 NOVEL SESQUITERPENOID STAT3 INHIBITORS UNIVERSITY OF HAWAII (US) 2014-12-24 WO disclosed
CN-103006647-B Use of 3-amido-2-pyridone derivative UNIV CHINA PHARMA 2014-09-10 CN disclosed
CN-103006647-A Use of 3-amido-2-pyridone derivative UNIV CHINA PHARMA 2013-04-03 CN disclosed
EP-1898908-B1 NOVEL CHEMICAL COMPOUNDS AND THE USES THEREOF AS A MEDICAMENT TROPHOS (FR) 2011-03-30 EP disclosed
US-7638505-B2 Organophosphoric derivatives useful as anti-parasitic agents UNIVERSITEIT GENT (BE) 2009-12-29 US disclosed
US-20090203747-A1 NOVEL CHEMICAL COMPOUNDS AND THE USES THEREOF AS A MEDICINE TROPHOS PARC SCIENTIFIQUE LUMINY (FR) 2009-08-13 US disclosed
US-20080312190-A1 Such as 3-(N-hydroxyacetamido)-1-(3,4-dichlorophenyl)propylphosphonic acid; Antimalaria agents UNIVERSITEIT GENT (BE) 2008-12-18 US disclosed
US-7449477-B2 7-phenyl-isoquinoline-5-sulfonylamino derivatives as inhibitors of akt (protein kinase B) ELI LILLY AND COMPANY (US) 2008-11-11 US disclosed
EP-1963344-A1 ORGANOPHOSPHORIC DERIVATIVES USEFUL AS ANTI-PARASITIC AGENTS UNIVERSITEIT GENT (BE) 2008-09-03 EP disclosed
EP-1898908-A2 NOVEL CHEMICAL COMPOUNDS AND THE USES THEREOF AS A MEDICAMENT Trophos (FR) 2008-03-19 EP disclosed
WO-2007071453-A1 ORGANOPHOSPHORIC DERIVATIVES USEFUL AS ANTI-PARASITIC AGENTS UNIVERSITEIT GENT (BE) 2007-06-28 WO disclosed
US-20070037796-A1 e.g. 7-Phenyl-isoquinoline-5-sulfonic acid {2-[3 -(4-nitrophenyl)-propylamino]-ethyl}-amide, dihydrochloride salt; antiviral, antineoplastic, anticarcinogenic agents; neoplasms ELI LILLY AND COMPANY 2007-02-15 US disclosed
WO-2007003767-A2 NOVEL CHEMICAL COMPOUNDS AND THE USES THEREOF AS A MEDICINE TROPHOS (FR) 2007-01-11 WO disclosed
CN-1294129-C Heteraryl-substituted porrole derivatives, their prep. and therapeutic use SANKYO CO (JP) 2007-01-10 CN disclosed
US-7122666-B2 Heteroaryl-substituted pyrrole derivatives, their preparation and their therapeutic uses SANKYO COMPANY, LIMITED (JP) 2006-10-17 US disclosed
CN-1274655-C Novel 3-aryl-2,5-dihydroxy-1,4-benzoquinone derivatives, their preparation method and pharmaceutical compositions containing same SERVIER LAB (FR) 2006-09-13 CN disclosed
US-20060128756-A1 Heteroaryl-substituted pyrrole derivatives, their preparation and their therapeutic uses SANKYO COMPANY, LIMITED (JP) 2006-06-15 US disclosed
US-20050283006-A1 Heteroaryl-substituted pyrrole derivatives, their preparation and their therapeutic uses SANKYO COMPANY, LIMITED (JP) 2005-12-22 US disclosed
CN-1628088-A Novel 3-aryl-2, 5-dihydroxy-1, 4-benzoquinones, process for preparing same and pharmaceutical compositions containing same SERVIER LAB (FR) 2005-06-15 CN disclosed
US-20050085644-A1 Novel 3-aryl-2,5-dihydroxy-1,4-benzoquinone derivatives, their preparation method and pharmaceutical compositions containing same LES LABORATOIRES SERVIER (FR) 2005-04-21 US disclosed
EP-1472208-A1 NOVEL 3-ARYL-2,5-DIHYDROXY-1,4-BENZOQUINONE DERIVATIVES, THEIR PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME LES LABORATOIRES SERVIER (FR) 2004-11-03 EP disclosed
CN-1525968-A composition for preventing or treating liver disease 三共株式会社 2004-09-01 CN disclosed
EP-0861864-B1 Method of preparation of polyquinolines HITACHI CHEMICAL CO LTD (JP) 2004-08-25 EP disclosed
EP-1070711-B1 Heteroaryl-substituted pyrrole derivatives, their preparation and their therapeutic uses SANKYO CO (JP) 2004-04-14 EP disclosed
US-20040054173-A1 Heteroaryl-substituted pyrrole derivatives, their preparation and their therapeutic uses SANKYO COMPANY, LIMITED (JP) 2004-03-18 US disclosed
US-6667346-B2 Administration of a radioprotective alpha, beta unsaturated aryl sulfone compound to a patient prior to anticancer radiotherapy reduces cytotoxic side effects of radiation on normal cells TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION 2003-12-23 US disclosed
EP-1352906-A1 COMPOSITIONS FOR PREVENTION OR TREATMENT OF HEPATOPATHY Sankyo Company, Limited (JP) 2003-10-15 EP disclosed
WO-2003066561-A1 NOVEL 3-ARYL-2,5-DIHYDROXY-1,4-BENZOQUINONE DERIVATIVES, THEIR PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME LES LABORATOIRES SERVIER (FR) 2003-08-14 WO disclosed
EP-1074550-B1 Process for the preparation of 3-substituted 4-phenyl-piperidine derivatives CHEMI SPA (IT) 2003-01-29 EP disclosed
EP-1243589-A1 Heteroaryl-substituted pyrrole derivates, their preparation and their therapeutic uses Sankyo Company Limited (JP) 2002-09-25 EP disclosed
US-6444822-B1 ANTIDEPRESSANTS CHEMI S.P.A. (IT) 2002-09-03 US disclosed
US-6306880-B1 HETEROCYCLIC ALCOHOL DERIVATIVES AS FUNGICIDES SANKYO COMPANY, LIMITED (JP) 2001-10-23 US disclosed
US-20010031768-A1 Triazole antifungal agent SANKYO COMPANY LIMITED (JP) 2001-10-18 US disclosed
US-20010031778-A1 Triazole antifungal agent SANKYO COMPANY LIMITED (JP) 2001-10-18 US disclosed
US-6300357-B1 FOR THERAPY OF MYCOTIC DISEASE OF A HUMAN BEING AND AN ANIMAL SANKYO COMPANY, LIMITED (JP) 2001-10-09 US disclosed
EP-0841327-B1 TRIAZOLE ANTIFUNGAL AGENT SANKYO CO (JP) 2001-10-04 EP disclosed
CN-1295069-A Heteraryl-substituted porrole derivatives, their prep. and therapeutic use SANKYO CO (JP) 2001-05-16 CN disclosed
EP-1074550-A1 Process for the preparation of 3-substituted 4-phenyl-piperidine derivatives CHEMI S.p.A. (IT) 2001-02-07 EP disclosed
EP-1070711-A2 Heteroaryl-substituted pyrrole derivatives, their preparation and their therapeutic uses Sankyo Company Limited (JP) 2001-01-24 EP disclosed
US-5977152-A Triazole antifungal agent SANKYO COMPANY, LIMITED (JP) 1999-11-02 US disclosed
EP-0861864-A2 Method of preparation of polyquinolines HITACHI CHEMICAL CO., LTD. (JP) 1998-09-02 EP disclosed
US-5786071-A Method of preparation of polyquinolines HITACHI CHEMICAL COMPANY, LTD. (JP) 1998-07-28 US disclosed
EP-0841327-A1 TRIAZOLE ANTIFUNGAL AGENT SANKYO COMPANY LIMITED (JP) 1998-05-13 EP disclosed
US-5723573-A ACETYLENIC END GROUPS HITACHI CHEMICAL COMPANY, LTD. (JP) 1998-03-03 US disclosed
US-5648448-A Method of preparation of polyquinolines HITACHI CHEMICAL COMPANY, LTD. (JP) 1997-07-15 US disclosed
US-5508412-A USED IN FORMATION OF UNSATURATED CYCLOHEXENONE OXIME ETHERS; HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1996-04-16 US disclosed
US-5407896-A Herbicides BASF AKTIENGESELLSCHAFT (DE) 1995-04-18 US disclosed
US-5403812-A Also containing a sulfur-containing ring; control of grasses but selective of broad-leaved and monocotyledonous crops BASF AKTIENGESELLSCHAFT (DE) 1995-04-04 US disclosed
US-4880624-A GUAIACOL, TRIMETHOXYBENZENE THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 1989-11-14 US disclosed
US-4282251-A FUNGICIDES SANDOZ LTD. (CH) 1981-08-04 US disclosed
US-4160036-A ADRENERGIC STIMULANTS ALLEN & HANBURYS LIMITED (GB) 1979-07-03 US disclosed
US-4012377-A ANTIMICROBIAL, PARASITICIDES GLAXO LABORATORIES LIMITED (EN) 1977-03-15 US disclosed
US-4012377-A ANTIMICROBIAL, PARASITICIDES GLAXO LABORATORIES LIMITED (EN) 1977-03-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (37 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170158638-A1 PIPERIDINONE HERBICIDES CYP1A1, CYP1B1, ARG1 ALDH1A1 59/4885KDM4E 1751/4885MAPT 4336/4885
US-10035800-B2 Substituted 1,4,10-triazadibenzo[cd,f]azulenes, substituted 1,4,5,10-tetraazadibenzo[cd,f]azulenes and substituted 1,4,5,7,10-pentaazadibenzo[cd,f]azulenes as bromodomain inhibitors BRD1, BRD3, BRD4 ALDH1A1 332/4885KDM4E 938/4885MAPT 3305/4885
US-20170247383-A1 NEUROACTIVE COMPOUNDS AND METHODS OF USING THE SAME GAP43, PNMT, SLC6A3 ALDH1A1 281/4885KDM4E 2259/4885MAPT 807/4885
US-20180298003-A1 TETRACYCLIC BROMODOMAIN INHIBITORS BRD3, BRD4, BRD1 ALDH1A1 2163/4885KDM4E 1602/4885MAPT 1302/4885
US-20200079784-A1 Compounds, Compositions and Methods BAX, CASP3, CASP8 ALDH1A1 3491/4885KDM4E 4338/4885MAPT 1091/4885
US-20230121698-A1 ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE 1 (ENPP1) MODULATORS AND USES THEREOF ENPP1, ENPP3, PPA1 ALDH1A1 2462/4885KDM4E 3548/4885MAPT 4401/4885
US-20180353480-A1 ISOXAZOLIDINE DERIVED INHIBITORS OF RECEPTOR INTERACTING PROTEIN KINASE 1 (RIPK1) RIPK1, RIPK2, RIPK3 ALDH1A1 4555/4885KDM4E 4151/4885MAPT 3759/4885
US-20200291027-A1 TETRACYCLIC BROMODOMAIN INHIBITORS BRD3, BRD4, BRD1 ALDH1A1 2163/4885KDM4E 1602/4885MAPT 1302/4885
US-20210070756-A1 TETRACYCLIC BROMODOMAIN INHIBITORS BRD3, BRD4, BRD1 ALDH1A1 2163/4885KDM4E 1602/4885MAPT 1302/4885
US-20010031768-A1 Triazole antifungal agent ERG28, RIF1, NAT1 ALDH1A1 1123/4885KDM4E 2229/4885MAPT 3625/4885
US-10800790-B2 Sesquiterpenoid STAT3 inhibitors STAT3, JAK2, STAT6 ALDH1A1 1903/4885KDM4E 2624/4885MAPT 4453/4885
US-12043602-B2 Fendiline derivatives CYP11B2, CYP3A7, CYP4F2 ALDH1A1 292/4885KDM4E 2954/4885MAPT 2791/4885
US-20070037796-A1 e.g. 7-Phenyl-isoquinoline-5-sulfonic acid {2-[3 -(4-nitrophenyl)-propylamino]-ethyl}-amide, dihydrochloride salt; antiviral, antineoplastic, anticarcinogenic agents; neoplasms POLI, HRAS, CHUK ALDH1A1 1956/4885KDM4E 2390/4885MAPT 4743/4885
US-20160296499-A1 Spiroindoline Antiparasitic Derivatives PKD2, PKD1, AVPR2 ALDH1A1 178/4885KDM4E 3461/4885MAPT 4482/4885
US-20220024938-A1 Compounds, Compositions and Methods BAX, CASP3, CASP8 ALDH1A1 3491/4885KDM4E 4338/4885MAPT 1091/4885
US-20160214951-A1 EBI2 MODULATORS BIRC2, HAVCR2, MAVS ALDH1A1 4277/4885KDM4E 1496/4885MAPT 3773/4885
US-20060128756-A1 Heteroaryl-substituted pyrrole derivatives, their preparation and their therapeutic uses IL2, IL1A, IL1B ALDH1A1 871/4885KDM4E 4073/4885MAPT 4733/4885
US-20220177440-A1 Fendiline Derivatives CYP11B2, CYP3A7, CYP4F2 ALDH1A1 292/4885KDM4E 2954/4885MAPT 2791/4885
US-20050283006-A1 Heteroaryl-substituted pyrrole derivatives, their preparation and their therapeutic uses IL2, CNKSR1, IL1A ALDH1A1 928/4885KDM4E 3407/4885MAPT 4699/4885
US-10301318-B2 Neuroactive compounds and methods of using the same GAP43, PNMT, SLC6A3 ALDH1A1 281/4885KDM4E 2259/4885MAPT 807/4885
US-20050085644-A1 Novel 3-aryl-2,5-dihydroxy-1,4-benzoquinone derivatives, their preparation method and pharmaceutical compositions containing same GPR119, UGT1A1, UGT1A3 ALDH1A1 329/4885KDM4E 2279/4885MAPT 4577/4885
US-10709692-B2 Isoxazolidine derived inhibitors of receptor interacting protein kinase 1 (RIPK1) RIPK1, RIPK2, RIPK3 ALDH1A1 4555/4885KDM4E 4151/4885MAPT 3759/4885
US-20150011620-A1 ANTI-INVASIVE COMPOUNDS MMP3, MMP10, MIF ALDH1A1 2677/4885KDM4E 2604/4885MAPT 3571/4885
US-10570129-B2 Carboline antiparasitics ADRA1D, DRD1, CHRM1 ALDH1A1 381/4885KDM4E 3087/4885MAPT 4298/4885
US-20150210640-A1 1-(CYCLOALKYL-CARBONYL)PROLINE DERIVATIVE RB1, F2, SFPQ ALDH1A1 3043/4885KDM4E 688/4885MAPT 4798/4885
US-11174262-B2 Compounds, compositions and methods BAX, CASP3, CASP8 ALDH1A1 3491/4885KDM4E 4338/4885MAPT 1091/4885
US-20170022218-A1 CONDENSED 5-OXAZOLIDINONE DERIVATIVE F2, SERPINC1, F12 ALDH1A1 414/4885KDM4E 3853/4885MAPT 4841/4885
US-20160137663-A1 NOVEL SESQUITERPENOID STAT3 INHIBITORS STAT3, JAK2, STAT6 ALDH1A1 2028/4885KDM4E 2666/4885MAPT 4358/4885
US-20190337956-A1 NEUROACTIVE COMPOUNDS AND METHODS OF USING SAME GAP43, OPRL1, SLC6A3 ALDH1A1 433/4885KDM4E 3916/4885MAPT 662/4885
US-20040054173-A1 Heteroaryl-substituted pyrrole derivatives, their preparation and their therapeutic uses IL2, IL1B, IL1A ALDH1A1 1023/4885KDM4E 3733/4885MAPT 4831/4885
US-20250034121-A1 COMPOUNDS AND THEIR USES AS GPR183 INHIBITORS GPR183, GPR180, GPR65 ALDH1A1 4198/4885KDM4E 4149/4885MAPT 3530/4885
US-20080312190-A1 Such as 3-(N-hydroxyacetamido)-1-(3,4-dichlorophenyl)propylphosphonic acid; Antimalaria agents SUB1, CBR1, NAT1 ALDH1A1 1560/4885KDM4E 3301/4885MAPT 4756/4885
US-20010031778-A1 Triazole antifungal agent ERG28, NAT1, RIF1 ALDH1A1 893/4885KDM4E 2992/4885MAPT 2797/4885
US-20190315691-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF PAROXETINE AND ITS INTERMEDIATE CYP2D6, CYP2C19, CYP2B6 ALDH1A1 605/4885KDM4E 875/4885MAPT 2870/4885
US-20200031822-A1 CARBOLINE ANTIPARASITICS DRD1, ADRA1D, DRD2 ALDH1A1 334/4885KDM4E 3549/4885MAPT 4336/4885
US-11851433-B2 Compounds, compositions and methods BAX, CASP3, CASP8 ALDH1A1 3491/4885KDM4E 4338/4885MAPT 1091/4885
US-20090203747-A1 NOVEL CHEMICAL COMPOUNDS AND THE USES THEREOF AS A MEDICINE NLN, NQO1, APP ALDH1A1 625/4885KDM4E 2254/4885MAPT 31/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.