SCHEMBL14361007

SCHEMBL14361007

CC1(C)O[C@@H]2[C@H](O1)[C@@H](COC(=O)CCCC[C@@H]1SC[C@@H]3NC(=O)N[C@@H]31)O[C@H]2n1cnc2c(N)ncnc21

nearest known ligand 0.62

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HLCS P50747 3/20 0.62
HINT1 P49773 1/20 0.60
RXFP1 Q9HBX9 1/20 0.52
PI4KA P42356 1/20 0.52
PI4K2B Q8TCG2 1/20 0.52
PI4K2A Q9BTU6 1/20 0.52
PI4KB Q9UBF8 1/20 0.52
P2RX1 P51575 1/20 0.51
P2RX3 P56373 1/20 0.51
P2RX4 Q99571 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23982212 0.88 HLCS (0.77) HLCSHINT1
SCHEMBL23982126 0.88 HLCS (0.77) HLCSHINT1
SCHEMBL6709382 0.88 HLCS (0.77) HLCSHINT1
SCHEMBL30595941 0.86 HINT1 (0.62) HLCSHINT1PI4KAPI4K2BPI4K2A
SCHEMBL17666101 0.86 HINT1 (0.62) HLCSHINT1PI4KAPI4K2BPI4K2A
SCHEMBL23982182 0.86 HLCS (0.67) HLCSHINT1
SCHEMBL23982185 0.86 HLCS (0.67) HLCSHINT1
SCHEMBL17652467 0.85 HINT1 (0.62) HLCSHINT1PI4KAPI4K2BPI4K2A
SCHEMBL23982282 0.84 HLCS (0.63) HLCSHINT1
SCHEMBL20418955 0.84 HLCS (0.63) HLCSHINT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070258921-A1 PROCESS FOR DEPIGMENTING THE SKIN L'OREAL (FR) 2007-11-08 US disclosed
US-20070258921-A1 PROCESS FOR DEPIGMENTING THE SKIN L'OREAL (FR) 2007-11-08 US disclosed
EP-1847547-A1 Anti-wrinkle cosmetic composition L'Oréal (FR) 2007-10-24 EP disclosed
US-20070237734-A1 ANTI-WRINKLE COSMETIC COMPOSITION L'OREAL (FR) 2007-10-11 US disclosed
US-20070237734-A1 ANTI-WRINKLE COSMETIC COMPOSITION L'OREAL (FR) 2007-10-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070258921-A1 PROCESS FOR DEPIGMENTING THE SKIN TYR, CUTA, NQO1 HLCS 3322/4885HINT1 1221/4885RXFP1 4558/4885
US-20070237734-A1 ANTI-WRINKLE COSMETIC COMPOSITION ADORA2A, ADORA3, ADORA1 HLCS 3872/4885HINT1 250/4885RXFP1 1013/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.