Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 10/20 | 0.54 |
| ▸ | MGAM | O43451 | 9/20 | 0.54 |
| ▸ | AMY1A | P0DUB6 | 9/20 | 0.54 |
| ▸ | SI | P14410 | 9/20 | 0.54 |
| ▸ | MGAM2 | Q2M2H8 | 9/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | F2 | P00734 | 2/20 | 0.54 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15426053 | 0.84 | DGAT1 (0.66) | DGAT1GAAMGAMAMY1ASI | |
| SCHEMBL5490033 | 0.82 | GAA (0.62) | DGAT1GAAMGAMAMY1ASI | |
| SCHEMBL18675329 | 0.81 | DGAT1 (0.61) | DGAT1GAAMGAMAMY1ASI | |
| SCHEMBL15426052 | 0.81 | DGAT1 (0.61) | DGAT1GAAMGAMAMY1ASI | |
| SCHEMBL29163194 | 0.81 | DGAT1 (0.61) | DGAT1GAAMGAMAMY1ASI | |
| SCHEMBL535054 | 0.81 | GAA (0.64) | DGAT1GAAMGAMAMY1ASI | |
| SCHEMBL18526054 | 0.81 | DGAT1 (0.61) | DGAT1GAAMGAMAMY1ASI | |
| SCHEMBL15218673 | 0.81 | DGAT1 (0.72) | DGAT1GAAMGAMAMY1ASI | |
| SCHEMBL16451454 | 0.80 | DGAT1 (0.56) | DGAT1GAAMGAMAMY1ASI | |
| SCHEMBL19496157 | 0.79 | DGAT1 (0.59) | DGAT1GAAMGAMAMY1ASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3450433-B1 | PURINE DERIVATIVES AS TLR7 INHIBITORS FOR TREATING E.G. SYSTEMIC LUPUS ERYTHEMATOSUS | SUMITOMO DAINIPPON PHARMA CO LTD (JP) | 2021-08-18 | — | — | EP | disclosed |
| EP-2751087-A1 | DIRECT SYNTHESIS OF 18F-FLUOROMETHOXY COMPOUNDS FOR PET IMAGING AND THE PROVISION OF NEW PRECURSORS FOR DIRECT RADIOSYNTHESIS OF PROTECTED DERIVATIVES OF O-([18F]FLUOROMETHYL)TYROSINE | Piramal Imaging SA (CH) | 2014-07-09 | — | — | EP | disclosed |
| WO-2013001088-A1 | DIRECT SYNTHESIS OF 18F-FLUOROMETHOXY COMPOUNDS FOR PET IMAGING AND THE PROVISION OF NEW PRECURSORS FOR DIRECT RADIOSYNTHESIS OF PROTECTED DERIVATIVES OF O-([18F]FLUOROMETHYL) TYROSINE | PIRAMAL IMAGING SA (CH) | 2013-01-03 | — | — | WO | disclosed |
| US-7199129-B2 | Derivatives of morphine-like opioid compounds | MONASH UNIVERSITY (AU) | 2007-04-03 | — | — | US | disclosed |