Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.56 |
| ▸ | SLC9A1 | P19634 | 5/20 | 0.51 |
| ▸ | GAA | P10253 | 10/20 | 0.50 |
| ▸ | MGAM | O43451 | 9/20 | 0.50 |
| ▸ | AMY1A | P0DUB6 | 9/20 | 0.50 |
| ▸ | SI | P14410 | 9/20 | 0.50 |
| ▸ | MGAM2 | Q2M2H8 | 9/20 | 0.50 |
| ▸ | F2 | P00734 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14362020 | 0.80 | DGAT1 (0.61) | DGAT1SLC9A1GAAMGAMAMY1A | |
| SCHEMBL8228893 | 0.80 | DGAT1 (0.53) | DGAT1SLC9A1GAAMGAMAMY1A | |
| SCHEMBL15426053 | 0.80 | DGAT1 (0.66) | DGAT1SLC9A1GAAMGAMAMY1A | |
| SCHEMBL30219683 | 0.79 | GAA (0.58) | DGAT1SLC9A1GAAMGAMAMY1A | |
| SCHEMBL13134139 | 0.79 | GAA (0.58) | DGAT1SLC9A1GAAMGAMAMY1A | |
| SCHEMBL18675329 | 0.77 | DGAT1 (0.61) | DGAT1SLC9A1GAAMGAMAMY1A | |
| SCHEMBL28836639 | 0.75 | DGAT1 (0.47) | DGAT1SLC9A1GAAMGAMAMY1A | |
| SCHEMBL29728229 | 0.75 | DGAT1 (0.47) | DGAT1SLC9A1GAAMGAMAMY1A | |
| SCHEMBL19496157 | 0.75 | DGAT1 (0.59) | DGAT1SLC9A1GAAMGAMAMY1A | |
| SCHEMBL17987937 | 0.75 | DGAT1 (0.59) | DGAT1SLC9A1GAAMGAMAMY1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9684293-B2 | Refrigerant relief valve monitoring system and method | BRT, LLC (US) | 2017-06-20 | — | — | US | disclosed |
| US-9233102-B2 | Methods and materials for treating cancer | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2016-01-12 | — | — | US | disclosed |
| US-20150045418-A1 | METHODS AND MATERIALS FOR TREATING CANCER | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH | 2015-02-12 | — | — | US | disclosed |