Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 9/20 | 0.54 |
| ▸ | MGAM | O43451 | 8/20 | 0.54 |
| ▸ | AMY1A | P0DUB6 | 8/20 | 0.54 |
| ▸ | SI | P14410 | 8/20 | 0.54 |
| ▸ | MGAM2 | Q2M2H8 | 8/20 | 0.54 |
| ▸ | F2 | P00734 | 2/20 | 0.54 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | F12 | P00748 | 6/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15426053 | 0.84 | DGAT1 (0.66) | DGAT1GAAMGAMAMY1ASI | |
| SCHEMBL14362020 | 0.81 | DGAT1 (0.61) | DGAT1GAAMGAMAMY1ASI | |
| SCHEMBL28952648 | 0.78 | GAA (0.65) | DGAT1GAAMGAMAMY1ASI | |
| SCHEMBL29728232 | 0.78 | GAA (0.65) | DGAT1GAAMGAMAMY1ASI | |
| SCHEMBL16451454 | 0.77 | DGAT1 (0.56) | DGAT1GAAMGAMAMY1ASI | |
| SCHEMBL29728231 | 0.76 | MGAM (0.68) | DGAT1GAAMGAMAMY1ASI | |
| SCHEMBL21203205 | 0.76 | DGAT1 (0.51) | DGAT1GAAMGAMAMY1ASI | |
| SCHEMBL28836685 | 0.76 | MGAM (0.68) | DGAT1GAAMGAMAMY1ASI | |
| SCHEMBL2970279 | 0.76 | DGAT1 (0.66) | DGAT1GAAMGAMAMY1ASI | |
| SCHEMBL706083 | 0.76 | MGAM (0.68) | DGAT1GAAMGAMAMY1ASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170088902-A1 | EXPRESSION PROFILING FOR CANCERS TREATED WITH ANTI-ANGIOGENIC THERAPY | ALMAC DIAGNOSTICS LIMITED (GB) | 2017-03-30 | — | — | US | disclosed |