Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | FAAH | O00519 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.53 |
| ▸ | FNTA | P49354 | 1/20 | 0.53 |
| ▸ | FNTB | P49356 | 1/20 | 0.53 |
| ▸ | RNF4 | P78317 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MITF | O75030 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9923545 | 0.89 | RAB9A (0.71) | RAB9ASMN1; SMN2ALDH1A1MAPTKMT2A | |
| SCHEMBL14363136 | 0.88 | MAPK1 (0.62) | RAB9AALDH1A1MAPTUSP2KMT2A | |
| SCHEMBL15474249 | 0.88 | USP2 (0.70) | RAB9ASMN1; SMN2ALDH1A1MAPTUSP2 | |
| SCHEMBL19322286 | 0.88 | RAB9A (0.64) | RAB9ASMN1; SMN2ALDH1A1MAPTUSP2 | |
| SCHEMBL27858337 | 0.87 | MEN1 (0.64) | RAB9ASMN1; SMN2ALDH1A1MAPTUSP2 | |
| SCHEMBL5464218 | 0.84 | USP2 (0.53) | RAB9ASMN1; SMN2ALDH1A1MAPTUSP2 | |
| SCHEMBL5184671 | 0.84 | HDAC1 (0.58) | RAB9ASMN1; SMN2ALDH1A1MAPTUSP2 | |
| SCHEMBL18657627 | 0.83 | RAB9A (0.74) | RAB9ASMN1; SMN2ALDH1A1MAPTUSP2 | |
| SCHEMBL257816 | 0.83 | EPHX2 (0.76) | RAB9ASMN1; SMN2ALDH1A1MAPTKMT2A | |
| SCHEMBL27858328 | 0.83 | ALDH1A1 (0.62) | RAB9ASMN1; SMN2ALDH1A1MAPTFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070276011-A1 | Plasminogen Activator Inhibitor-1 Inhibitor | INSTITUTE OF MEDICINAL MOLECULAR DESIGN. INC. (JP) | 2007-11-29 | — | — | US | disclosed |
| US-20070276011-A1 | Plasminogen Activator Inhibitor-1 Inhibitor | INSTITUTE OF MEDICINAL MOLECULAR DESIGN. INC. (JP) | 2007-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070276011-A1 | Plasminogen Activator Inhibitor-1 Inhibitor | SERPINE1, SERPINC1, SERPINB1 | RAB9A 3765/4885SMN1; SMN2 2862/4885ALDH1A1 1861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.