Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.60 |
| ▸ | SRC | P12931 | 1/20 | 0.59 |
| ▸ | P2RX1 | P51575 | 4/20 | 0.58 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.58 |
| ▸ | GRM5 | P41594 | 1/20 | 0.58 |
| ▸ | PLAU | P00749 | 2/20 | 0.57 |
| ▸ | F2 | P00734 | 1/20 | 0.57 |
| ▸ | F10 | P00742 | 1/20 | 0.57 |
| ▸ | PLAT | P00750 | 1/20 | 0.57 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.56 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6285639 | 0.86 | TMPRSS4 (0.67) | P2RX1TMPRSS4GRM5PLAUF2 | |
| SCHEMBL14363294 | 0.84 | NPC1 (0.60) | P2RX1TMPRSS4GRM5PLAUF2 | |
| SCHEMBL14363185 | 0.83 | FADS1 (0.67) | P2RX1MEN1KMT2AALDH1A1NLRP3 | |
| SCHEMBL11761072 | 0.83 | MAPT (0.61) | P2RX1TMPRSS4GRM5PLAUF2 | |
| SCHEMBL14363184 | 0.83 | PLAU (0.69) | MAOBP2RX1TMPRSS4GRM5PLAU | |
| SCHEMBL14363179 | 0.83 | PLAU (0.65) | P2RX1TMPRSS4GRM5PLAUF2 | |
| SCHEMBL21021862 | 0.82 | PLAU (0.73) | P2RX1TMPRSS4GRM5PLAUF2 | |
| SCHEMBL14394718 | 0.82 | P2RX1 (0.78) | P2RX1TMPRSS4P2RX4P2RX7MEN1 | |
| SCHEMBL14363287 | 0.82 | GPR17 (0.63) | P2RX1TMPRSS4GRM5PLAUF2 | |
| SCHEMBL14363303 | 0.81 | P2RX1 (0.73) | P2RX1MEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070276011-A1 | Plasminogen Activator Inhibitor-1 Inhibitor | INSTITUTE OF MEDICINAL MOLECULAR DESIGN. INC. (JP) | 2007-11-29 | — | — | US | disclosed |
| US-20070276011-A1 | Plasminogen Activator Inhibitor-1 Inhibitor | INSTITUTE OF MEDICINAL MOLECULAR DESIGN. INC. (JP) | 2007-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070276011-A1 | Plasminogen Activator Inhibitor-1 Inhibitor | SERPINE1, SERPINC1, SERPINB1 | MAOB 682/4885SRC 1231/4885P2RX1 4478/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.