Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 4/20 | 0.50 |
| ▸ | CSGALNACT1 | Q8TDX6 | 1/20 | 0.47 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1761473 | 0.92 | DGAT1 (0.57) | DGAT1CSGALNACT1PDPK1DYRK1AMAPT | |
| SCHEMBL1761583 | 0.90 | DGAT1 (0.53) | DGAT1CSGALNACT1PTGESPDPK1DYRK1A | |
| SCHEMBL1761710 | 0.88 | DGAT1 (0.51) | DGAT1CSGALNACT1PTGESPDPK1DYRK1A | |
| SCHEMBL1761373 | 0.88 | DGAT1 (0.51) | DGAT1CSGALNACT1PTGESPDPK1DYRK1A | |
| SCHEMBL1761375 | 0.85 | DGAT1 (0.56) | DGAT1CSGALNACT1PTGESMAPTSMN1; SMN2 | |
| SCHEMBL1761566 | 0.84 | DGAT1 (0.66) | DGAT1CSGALNACT1PDPK1DYRK1AMAPT | |
| SCHEMBL1761555 | 0.83 | DGAT1 (0.53) | DGAT1CSGALNACT1PTGESPDPK1DYRK1A | |
| SCHEMBL1761463 | 0.83 | DGAT1 (0.51) | DGAT1CSGALNACT1PTGESPDPK1DYRK1A | |
| SCHEMBL1761387 | 0.82 | DGAT1 (0.49) | DGAT1CSGALNACT1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL1761722 | 0.82 | DGAT1 (0.50) | DGAT1CSGALNACT1PTGESMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070265298-A1 | Preparation and Use of Biphenyl-4-Yl-Carbonylamino Acid Derivatives for the Treatment of Obesity | BAYER PHARMACEUTICALS CORPORATION (US) | 2007-11-15 | — | — | US | disclosed |
| US-20070265298-A1 | Preparation and Use of Biphenyl-4-Yl-Carbonylamino Acid Derivatives for the Treatment of Obesity | BAYER PHARMACEUTICALS CORPORATION (US) | 2007-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070265298-A1 | Preparation and Use of Biphenyl-4-Yl-Carbonylamino Acid Derivatives for the Treatment of Obesity | FABP4, GPR119, PGC | DGAT1 486/4885CSGALNACT1 3157/4885PTGES 1595/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.