Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.55 |
| ▸ | CES1 | P23141 | 2/20 | 0.55 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.55 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17230531 | 0.84 | SMN1; SMN2 (0.58) | AKR1C3PTGS2PTGS1MAPTMEN1 | |
| SCHEMBL14393180 | 0.84 | CYP11B1 (0.48) | CYP11B1CYP11B2PTGS2MEN1KMT2A | |
| SCHEMBL3468454 | 0.82 | AKR1C3 (0.61) | AKR1C3PTGS2PTGS1MAPTMEN1 | |
| SCHEMBL19859448 | 0.80 | ENPP2 (0.47) | AKR1C3CYP11B1CYP11B2PTGS2KMT2A | |
| SCHEMBL280156 | 0.79 | PKM (0.70) | AKR1C3PTGS2PTGS1 | |
| SCHEMBL11986371 | 0.79 | PKM (0.70) | AKR1C3PTGS2PTGS1 | |
| SCHEMBL14367117 | 0.79 | CA1 (0.72) | CES2CES1MAPTMEN1KMT2A | |
| SCHEMBL14367103 | 0.75 | CES2 (0.55) | CES2CES1CYP11B1CYP11B2MAPT | |
| SCHEMBL19212940 | 0.75 | CYP11B1 (0.64) | AKR1C3CYP11B1CYP11B2PTGS2 | |
| SCHEMBL7090594 | 0.74 | CES2 (0.70) | CES2CES1PTGS2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7288360-B2 | Image recording material | FUJIFILM CORPORATION (JP) | 2007-10-30 | — | — | US | disclosed |