SCHEMBL280156

SCHEMBL280156

COc1ccc(S(C)(=O)=O)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 3/20 0.70
PTGS2 P35354 7/20 0.67
PTGS1 P23219 4/20 0.67
CA1 P00915 2/20 0.57
CA2 P00918 2/20 0.57
GAA P10253 2/20 0.57
MMP1 P03956 1/20 0.57
MMP2 P08253 1/20 0.57
MMP9 P14780 1/20 0.57
MMP8 P22894 1/20 0.57
MMP13 P45452 1/20 0.57
AKR1C3 P42330 1/20 0.56
NPC1 O15118 1/20 0.55
PKLR P30613 1/20 0.55
RAB9A P51151 1/20 0.55
CA12 O43570 1/20 0.55
CA7 P43166 1/20 0.55
CA9 Q16790 1/20 0.55
CA14 Q9ULX7 1/20 0.55
F2 P00734 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11986371 1.00 PKM (0.70) PKMPTGS2PTGS1CA1CA2
SCHEMBL7503391 0.93 PTGS2 (0.71) PKMPTGS2PTGS1
SCHEMBL8005674 0.93 PKM (0.61) PKMPTGS2PTGS1CA1CA2
SCHEMBL14097069 0.88 PTGS2 (0.65) PKMPTGS2PTGS1
SCHEMBL13924686 0.88 LMNA (0.60) PKMPTGS2PTGS1CA1CA2
SCHEMBL5798973 0.88 PTGS2 (0.60) PKMPTGS2PTGS1AKR1C3LMNA
SCHEMBL14097066 0.88 PKM (0.73) PKMPTGS2PTGS1GAAMMP2
SCHEMBL3468454 0.86 AKR1C3 (0.61) PKMPTGS2PTGS1GAAAKR1C3
SCHEMBL6725826 0.84 PTGS2 (0.77) PTGS2PTGS1
SCHEMBL31384620 0.84 PTGS2 (0.53) PKMPTGS2PTGS1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 523 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118763273-A Sulfonyl deep eutectic polymer electrolyte and preparation and application thereof 青岛赛锂达储能产业技术研究院有限公司 2024-10-11 CN claimed
CN-104531397-A Cleaning solution for sheet glass substrate thinning pre-cleaning, and application thereof HUIJING DISPLAY TECHNOLOGY SUZHOU CO LTD 2015-04-22 CN claimed
CN-102827042-A Chiral synthesis method of florfenicol HUBEI MASTEAM BIO TECHNOLOGY CO LTD 2012-12-19 CN claimed
EP-0929519-B1 BETA-SULFONYL HYDROXAMIC ACIDS AS MATRIX METALLOPROTEINASES INHIBITORS UPJOHN CO (US) 2005-02-23 EP claimed
EP-0960108-B1 MATRIX METALLOPROTEINASE INHIBITORS PHARMACIA ITALIA SPA (IT) 2004-10-27 EP claimed
US-6235928-B1 ENZYME INHIBITOR MATRIX METALLOPROTEINASE FAMILY, INCLUDING COLLAGENASE, STROMELYSIN, AND GELATINASE, THE COMPOUNDS OR PHARMACEUTICAL COMPOSITIONS PHARMACIA & UPJOHN COMPANY 2001-05-22 US claimed
US-6194451-B1 PREVENT RELEASE TUMOR NECROSIS FACTOR; ANTIINFLAMMATORY AGENTS PHARMACIA & UPJOHN S.P.A. (IT) 2001-02-27 US claimed
EP-0929519-A1 $g(b)-SULFONYL HYDROXAMIC ACIDS AS MATRIX METALLOPROTEINASES INHIBITORS PHARMACIA & UPJOHN COMPANY (US) 1999-07-21 EP claimed
US-5847153-A β-sulfonyl hydroxamic acids PHARMACIA & UPJOHN COMPANY (US) 1998-12-08 US claimed
WO-1998013340-A1 β-SULFONYL HYDROXAMIC ACIDS AS MATRIX METALLOPROTEINASES INHIBITORS PHARMACIA & UPJOHN COMPANY (US) 1998-04-02 WO claimed
WO-2026099505-A1 SYSTEM FOR CONTROLLING BATTERY TEMPERATURE NYOBOLT LIMITED (GB) 2026-05-15 WO disclosed
EP-4634118-B1 NIOBIUM METAL OXIDE NYOBOLT LTD (GB) 2026-04-22 EP disclosed
US-20260055083-A1 APOL1 INHIBITORS AND METHODS OF USE MAZE THERAPEUTICS INC (US) 2026-02-26 US disclosed
US-12478680-B2 Hydrogels with biodegradable crosslinking PROLYNX LLC (US) 2025-11-25 US disclosed
US-20250337004-A1 COMPOSITE POLYMER CERAMIC ELECTROLYTE HSBC VENTURES USA INC. 2025-10-30 US disclosed
US-5571660-A Method for forming an image KONICA CORPORATION (JP) 1996-11-05 US disclosed
EP-0642055-A1 A method of forming an image KONICA CORPORATION (JP) 1995-03-08 EP disclosed
EP-0337063-B1 Alkyl aryl sulfones and method of preparing the same ATOCHEM NORTH AMERICA (US) 1994-04-13 EP disclosed
US-5015775-A Alkyl aryl sulfones and method of preparing the same ATOCHEM NORTH AMERICA, INC. (US) 1991-05-14 US disclosed
EP-0337063-A1 Alkyl aryl sulfones and method of preparing the same ATOCHEM NORTH AMERICA, INC. (a Pennsylvania corp.) (US) 1989-10-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260055083-A1 APOL1 INHIBITORS AND METHODS OF USE APOL1, LDLR, APOB PKM 3915/4885PTGS2 4049/4885PTGS1 2658/4885
US-12478680-B2 Hydrogels with biodegradable crosslinking IDUA, APEH, GUSB PKM 1638/4885PTGS2 306/4885PTGS1 258/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.