Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16588044 | 0.89 | MAPT (0.53) | LMNAPOLBMAPTTP53TSHR | |
| SCHEMBL14564383 | 0.88 | PDE5A (0.48) | LMNAPOLBMAPTTP53KDM4E | |
| SCHEMBL5639547 | 0.85 | ATAD2 (0.44) | LMNAPOLBMAPTTP53ATAD2 | |
| SCHEMBL14564427 | 0.85 | TSHR (0.56) | LMNAPOLBMAPTTP53TSHR | |
| SCHEMBL5641249 | 0.82 | MAPT (0.58) | LMNAPOLBMAPTTP53MEN1 | |
| SCHEMBL5639284 | 0.81 | LMNA (0.50) | LMNAPOLBMAPTKMT2A | |
| SCHEMBL8699228 | 0.81 | SIRT2 (0.48) | LMNAPOLBMAPTATAD2MEN1 | |
| SCHEMBL6721642 | 0.78 | LMNA (0.43) | LMNAPOLBMAPTTP53KMT2A | |
| SCHEMBL435242 | 0.78 | ATAD2 (0.69) | LMNAPOLBMAPTTP53TSHR | |
| SCHEMBL2061713 | 0.78 | ATAD2 (0.54) | LMNAPOLBMAPTKDM4EATAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070265242-A1 | Novel Carbapenem Compound | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2007-11-15 | — | — | US | disclosed |
| US-20070265242-A1 | Novel Carbapenem Compound | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2007-11-15 | — | — | US | disclosed |
| US-20070054902-A1 | Isoxazole derivatives as peroxisome proliferator-activated receptors agonists | SHIONOGI & CO., LTD. (JP) | 2007-03-08 | — | — | US | disclosed |
| US-20070054902-A1 | Isoxazole derivatives as peroxisome proliferator-activated receptors agonists | SHIONOGI & CO., LTD. (JP) | 2007-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070265242-A1 | Novel Carbapenem Compound | C1R, C3AR1, OXA1L | LMNA 1288/4885POLB 2517/4885MAPT 4855/4885 |
| US-20070054902-A1 | Isoxazole derivatives as peroxisome proliferator-activated receptors agonists | NR1H3, NR1H2, RXRA | LMNA 4194/4885POLB 2010/4885MAPT 4429/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.