Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 3/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2061448 | 0.93 | POLB (0.45) | SIRT2MAPTNPC1MAPK1RAB9A | |
| SCHEMBL4385065 | 0.88 | PPARG (0.48) | SIRT2MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL2676069 | 0.86 | SIRT2 (0.51) | SIRT2MAPTALDH1A1GRIN1GRIN2B | |
| SCHEMBL14368232 | 0.81 | LMNA (0.53) | MAPTALDH1A1MEN1POLBKMT2A | |
| SCHEMBL8128306 | 0.81 | ATAD2 (0.61) | SIRT2MAPTNPC1MAPK1RAB9A | |
| SCHEMBL18421420 | 0.81 | GRIN1 (0.51) | SIRT2MAPTNPC1MAPK1RAB9A | |
| SCHEMBL5639547 | 0.80 | ATAD2 (0.44) | MAPTALDH1A1POLBLMNAATAD2 | |
| SCHEMBL10129647 | 0.79 | PPARG (0.48) | MAPTRAB9AALDH1A1GRIN1GRIN2B | |
| SCHEMBL20162398 | 0.79 | GRIN1 (0.54) | SIRT2MAPTALDH1A1GRIN1GRIN2B | |
| SCHEMBL5639284 | 0.79 | LMNA (0.50) | MAPTPOLBKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5780480-A | THROMBOLYTIC AGENTS, ANTICOAGULANTS | MERCK & CO., INC. (US) | 1998-07-14 | — | — | US | disclosed |