Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 2/20 | 0.50 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.50 |
| ▸ | GSK3B | P49841 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 2/20 | 0.41 |
| ▸ | NOS1 | P29475 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10298149 | 0.87 | ABCC9 (0.41) | ABCC9KCNJ11GSK3BCA2CA1 | |
| SCHEMBL14378468 | 0.82 | LMNA (0.51) | ABCC9KCNJ11GSK3BCA2CA1 | |
| SCHEMBL24769300 | 0.72 | ESR1 (0.44) | CA2CA1ALDH1A1CYP2A6LMNA | |
| SCHEMBL13013670 | 0.72 | CA2 (0.48) | GSK3BCA2CA1MEN1KMT2A | |
| SCHEMBL9559757 | 0.71 | GSK3B (0.61) | GSK3BCA2CA1MEN1KMT2A | |
| SCHEMBL11437264 | 0.71 | GSK3B (0.43) | ABCC9KCNJ11GSK3BCA2CA1 | |
| SCHEMBL1226232 | 0.69 | GSK3B (0.66) | GSK3BCA2CA1MEN1KMT2A | |
| SCHEMBL518003 | 0.69 | CA2 (0.54) | GSK3BCA2CA1ALDH1A1CYP2A6 | |
| SCHEMBL21783612 | 0.68 | CA2 (0.58) | GSK3BCA2CA1ALDH1A1CYP2A6 | |
| SCHEMBL4078022 | 0.68 | CA2 (0.58) | GSK3BCA2CA1ALDH1A1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007127440-A2 | HETEROFUNCTIONAL POLY(ETHYLENE GLYCOL) CONTAINING ACID-LABILE AMINO PROTECTING GROUPS AND USES THEREOF | INTEZYNE TECHNOLOGIES, INC. (US) | 2007-11-08 | — | — | WO | disclosed |