SCHEMBL143838

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1640595	0.82	CYP3A4 (0.49)	CYP3A4ACHECYP1A2CA12CA1
	SCHEMBL21416048	0.82	KDM4E (0.59)	CYP3A4CYP1A2CA12CA1CA2
	SCHEMBL27980095	0.81	CYP3A4 (0.51)	CYP3A4ACHECYP1A2CA12CA1
	SCHEMBL21416134	0.78	ALDH1A1 (0.39)	CYP3A4ACHECA12CA1CA2
	SCHEMBL1328619	0.76	CYP3A4 (0.42)	CYP3A4ACHECYP1A2CA12CA1
	SCHEMBL13743871	0.70	KDM4E (0.71)	CYP3A4ACHECYP1A2CA12CA1
	SCHEMBL725269	0.69	CYP3A4 (0.77)	CYP3A4ACHECA12CA1CA2
	SCHEMBL1636307	0.67	CYP3A4 (0.62)	CYP3A4ACHECA12CA1CA2
	SCHEMBL8549690	0.67	CYP3A4 (0.47)	CYP3A4ACHECA12CA1CA2
	SCHEMBL22491120	0.67	GAA (0.50)	CYP3A4ACHECA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.