Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.64 |
| ▸ | TPMT | P51580 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | APEX1 | P27695 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9695064 | 0.88 | TPMT (0.58) | TDP1TPMTHSD17B10ALOX15ALOX12 | |
| SCHEMBL129971 | 0.86 | ALOX15 (0.56) | TDP1TPMTALOX15ALOX12MAPT | |
| SCHEMBL16904136 | 0.86 | TDP1 (0.48) | TDP1TPMTHSD17B10ALOX15ALOX12 | |
| SCHEMBL30927163 | 0.86 | ALOX15 (0.56) | TDP1TPMTALOX15ALOX12MAPT | |
| SCHEMBL21823580 | 0.84 | TPMT (0.55) | TDP1TPMTHSD17B10ALOX15ALOX12 | |
| SCHEMBL16596078 | 0.84 | TDP1 (0.46) | TDP1TPMTHSD17B10ALOX15ALOX12 | |
| SCHEMBL10355393 | 0.80 | HSD17B10 (0.71) | TDP1TPMTHSD17B10MAPTKDM4E | |
| SCHEMBL14385352 | 0.78 | ALOX15 (0.62) | TDP1TPMTHSD17B10ALOX15ALOX12 | |
| Iretol SCHEMBL3190103 | 0.78 | TDP1 (1.00) | TDP1TPMTMAPTCYP3A4CA2 | |
| SCHEMBL2086471 | 0.77 | TPMT (0.62) | TDP1TPMTHSD17B10MAPTERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0471941-A2 | An improved process for the preparation of 5-bromo-2-methoxyresorcinol | AMERICAN CYANAMID COMPANY (US) | 1992-02-26 | — | — | EP | claimed |
| JP-6321839-A | — | — | None | — | — | JP | disclosed |
| WO-2013026942-A1 | TUBULIN BINDING AGENTS | THE PROVOST, FELLOWS, FOUNDATION SCHOLARS, AND THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH, NEAR DUBLIN (IE) | 2013-02-28 | — | — | WO | disclosed |
| WO-2013026942-A1 | TUBULIN BINDING AGENTS | THE PROVOST, FELLOWS, FOUNDATION SCHOLARS, AND THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH, NEAR DUBLIN (IE) | 2013-02-28 | — | — | WO | disclosed |
| JP-H06321839-A | IMPROVED PROCESS FOR PREPARATION OF 5-BROMO-2-METHOXYRESORCINOL | AMERICAN CYANAMID CO | 1994-11-22 | — | — | JP | disclosed |
| EP-0471941-A2 | An improved process for the preparation of 5-bromo-2-methoxyresorcinol | AMERICAN CYANAMID COMPANY (US) | 1992-02-26 | — | — | EP | disclosed |
| EP-0471941-A2 | An improved process for the preparation of 5-bromo-2-methoxyresorcinol | AMERICAN CYANAMID COMPANY (US) | 1992-02-26 | — | — | EP | disclosed |
| EP-0471941-A2 | An improved process for the preparation of 5-bromo-2-methoxyresorcinol | AMERICAN CYANAMID COMPANY (US) | 1992-02-26 | — | — | EP | disclosed |