Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | SQOR | Q9Y6N5 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14385873 | 0.93 | PIM1 (0.40) | HPGDNPSR1ADORA2AADORA1SQOR | |
| SCHEMBL14385841 | 0.88 | SQOR (0.37) | KDM4EHPGDPPARGNCOA2NCOA1 | |
| SCHEMBL14385270 | 0.83 | KMT2A (0.40) | KDM4EHPGDNPSR1ADORA2AADORA1 | |
| SCHEMBL14385248 | 0.79 | KDM4E (0.61) | KDM4EHPGDPPARGNCOA2NCOA1 | |
| SCHEMBL5414611 | 0.78 | HPGD (0.54) | KDM4EHPGDPPARGNCOA2NCOA1 | |
| SCHEMBL14385243 | 0.75 | SQOR (0.38) | KDM4EHPGDNPSR1SQORGAA | |
| SCHEMBL14385829 | 0.74 | SQOR (0.49) | KDM4EHPGDNPSR1SQORMAPT | |
| SCHEMBL14385643 | 0.74 | ALDH1A1 (0.38) | KDM4EHPGDPPARGNCOA2NCOA1 | |
| SCHEMBL14385648 | 0.74 | SQOR (0.63) | KDM4EHPGDNPSR1ADORA2AADORA1 | |
| SCHEMBL8401200 | 0.71 | L3MBTL1 (0.49) | KDM4EHPGDPPARGNCOA2NCOA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007124545-A1 | INTEGRASE INHIBITORS - 2 | AVEXA LIMITED (AU) | 2007-11-08 | — | — | WO | disclosed |