Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12432115 | 0.89 | PYCR1 (0.32) | HSD11B1 | |
| SCHEMBL14386160 | 0.89 | OPRM1 (0.35) | HSD11B1METAP1 | |
| SCHEMBL12432125 | 0.81 | OPRM1 (0.33) | HSD11B1 | |
| SCHEMBL12432116 | 0.80 | P2RX7 (0.33) | HSD11B1METAP1 | |
| SCHEMBL14386159 | 0.79 | HSD11B1 (0.32) | HSD11B1 | |
| SCHEMBL12432106 | 0.79 | P2RX7 (0.36) | — | |
| SCHEMBL2208101 | 0.78 | HSD11B1 (0.41) | HSD11B1 | |
| SCHEMBL12432112 | 0.78 | OPRM1 (0.36) | HSD11B1METAP1 | |
| SCHEMBL2990822 | 0.75 | HSD11B1 (0.54) | HSD11B1 | |
| SCHEMBL474663 | 0.74 | HSD11B1 (0.41) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007124254-A2 | CYCLOHEXYLPYRAZOLE-LACTAM DERIVATIVES AS INHIBITORS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE 1 | ELI LILLY AND COMPANY (US) | 2007-11-01 | — | — | WO | disclosed |