Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | MC4R | P32245 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | CKS1B | P61024 | 2/20 | 0.43 |
| ▸ | SKP1 | P63208 | 2/20 | 0.43 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.43 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.41 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.41 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5332037 | 0.87 | MC4R (0.54) | OPRD1OPRK1MC4RACHECKS1B | |
| SCHEMBL5337806 | 0.86 | OPRD1 (0.48) | OPRD1OPRK1MC4RACHECKS1B | |
| SCHEMBL5337967 | 0.84 | OPRD1 (0.47) | OPRD1OPRK1MC4RACHECKS1B | |
| SCHEMBL14387785 | 0.82 | OPRD1 (0.46) | OPRD1OPRK1MC4RACHECKS1B | |
| SCHEMBL14355809 | 0.81 | BRD9 (0.45) | MC4R | |
| SCHEMBL5343839 | 0.78 | ACHE (0.48) | OPRD1OPRK1ACHECKS1BSKP1 | |
| SCHEMBL7981893 | 0.78 | GAA (0.56) | ACHECKS1BSKP1SKP2GPR119 | |
| SCHEMBL5335315 | 0.77 | MC4R (0.53) | MC4RACHECKS1BSKP1SKP2 | |
| SCHEMBL28708137 | 0.77 | GPR119 (0.49) | ACHECKS1BSKP1SKP2GPR119 | |
| SCHEMBL5333697 | 0.76 | ACHE (0.48) | ACHECKS1BSKP1SKP2PLA2G7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291619-B2 | Melanocortin receptor agonists | ELI LILLY AND COMPANY (US) | 2007-11-06 | — | — | US | disclosed |