Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD9 | Q9H8M2 | 6/20 | 0.45 |
| ▸ | BRPF1 | P55201 | 3/20 | 0.45 |
| ▸ | NCF1 | P14598 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 3/20 | 0.43 |
| ▸ | DRD3 | P35462 | 3/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | MC4R | P32245 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 2/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.40 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14355971 | 0.86 | HTR6 (0.49) | DRD2DRD3HTR1ADRD4HTR2A | |
| SCHEMBL14355806 | 0.83 | MC4R (0.50) | BRD9BRPF1NCF1DRD2DRD3 | |
| SCHEMBL14355815 | 0.82 | DRD2 (0.51) | BRD9BRPF1NCF1DRD2DRD3 | |
| SCHEMBL14387751 | 0.81 | OPRD1 (0.47) | MC4R | |
| SCHEMBL14355811 | 0.78 | DRD2 (0.44) | BRD9BRPF1NCF1DRD2DRD3 | |
| SCHEMBL14355877 | 0.73 | NCF1 (0.51) | BRD9BRPF1NCF1DRD2DRD3 | |
| SCHEMBL15928086 | 0.72 | TDP1 (0.54) | CYP2D6TSHRCYP2C19HIF1AKCNH2 | |
| SCHEMBL14355793 | 0.71 | CYP11B1 (0.56) | BRD9BRPF1NCF1DRD2DRD3 | |
| SCHEMBL9341301 | 0.70 | TDP1 (0.58) | CYP2D6TSHRCYP2C19HIF1AKCNH2 | |
| SCHEMBL18781674 | 0.70 | NCF1 (0.58) | BRD9BRPF1NCF1DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291619-B2 | Melanocortin receptor agonists | ELI LILLY AND COMPANY (US) | 2007-11-06 | — | — | US | disclosed |