Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 2/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14390900 | 0.92 | MRGPRX4 (0.41) | ALOX5APFEN1GSTM2MRGPRX4 | |
| SCHEMBL3635397 | 0.88 | KDM4E (0.44) | GSTM2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL14392313 | 0.87 | ALDH1A1 (0.34) | — | |
| SCHEMBL3592409 | 0.80 | CYP2C19 (0.49) | ALOX5APFEN1MRGPRX4 | |
| SCHEMBL14390696 | 0.79 | MEN1 (0.36) | LMNA | |
| SCHEMBL14392510 | 0.79 | ALDH1A1 (0.39) | LMNA | |
| SCHEMBL14390693 | 0.78 | ACMSD (0.46) | ALOX5APFEN1MRGPRX4 | |
| SCHEMBL14390996 | 0.77 | ADORA2A (0.39) | ALOX5APFEN1LMNA | |
| SCHEMBL14391095 | 0.76 | GAA (0.39) | — | |
| SCHEMBL14391001 | 0.75 | ADORA2A (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007124546-A1 | INTEGRASE INHIBITORS 3 | AVEXA LIMITED (AU) | 2007-11-08 | — | — | WO | disclosed |