Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.40 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CLK1 | P49759 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.33 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | MPO | P05164 | 1/20 | 0.33 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14390892 | 0.92 | ALOX5AP (0.36) | MRGPRX4ALOX5APFEN1GSTM2 | |
| SCHEMBL3592409 | 0.89 | CYP2C19 (0.49) | MRGPRX4ALOX5APFEN1CYP2C19ACMSD | |
| SCHEMBL14392313 | 0.85 | ALDH1A1 (0.34) | CYP2C19CYSLTR2CYSLTR1 | |
| SCHEMBL14390693 | 0.81 | ACMSD (0.46) | MRGPRX4ALOX5APFEN1ACMSD | |
| SCHEMBL14390996 | 0.80 | ADORA2A (0.39) | ALOX5APFEN1CYP2C19 | |
| SCHEMBL3635397 | 0.80 | KDM4E (0.44) | CYP2C19ACMSDGSTM2 | |
| SCHEMBL14392510 | 0.77 | ALDH1A1 (0.39) | CYP2C19NPC1 | |
| SCHEMBL14390696 | 0.74 | MEN1 (0.36) | CYP2C19NPC1 | |
| SCHEMBL14392254 | 0.73 | HPGD (0.34) | — | |
| SCHEMBL14390898 | 0.73 | KMT2A (0.40) | RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007124546-A1 | INTEGRASE INHIBITORS 3 | AVEXA LIMITED (AU) | 2007-11-08 | — | — | WO | disclosed |