Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | USP2 | O75604 | 4/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 6/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14391095 | 0.88 | GAA (0.39) | MEN1KMT2AGAAPOLBALDH1A1 | |
| SCHEMBL14390892 | 0.79 | ALOX5AP (0.36) | LMNA | |
| SCHEMBL14390693 | 0.79 | ACMSD (0.46) | HPGD | |
| SCHEMBL14392510 | 0.78 | ALDH1A1 (0.39) | MEN1KMT2AGAAPOLBALDH1A1 | |
| SCHEMBL14390898 | 0.76 | KMT2A (0.40) | MEN1KMT2AGAAPOLBALDH1A1 | |
| SCHEMBL14390902 | 0.76 | HPGD (0.36) | MEN1KMT2AGAAPOLBALDH1A1 | |
| SCHEMBL14390996 | 0.76 | ADORA2A (0.39) | MEN1KMT2AGAAALDH1A1KDM4E | |
| SCHEMBL14391001 | 0.74 | ADORA2A (0.47) | MEN1KMT2AGAAPOLBALDH1A1 | |
| SCHEMBL14390900 | 0.74 | MRGPRX4 (0.41) | CYP2C19NPC1 | |
| SCHEMBL14392313 | 0.74 | ALDH1A1 (0.34) | MEN1KMT2AGAAPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007124546-A1 | INTEGRASE INHIBITORS 3 | AVEXA LIMITED (AU) | 2007-11-08 | — | — | WO | disclosed |