Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.44 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3590231 | 0.88 | ALDH1A1 (0.56) | SMN1; SMN2NPC1RAB9APOLBMAPT | |
| SCHEMBL3597920 | 0.80 | ALDH1A1 (0.55) | SMN1; SMN2NPC1RAB9APOLBMAPT | |
| SCHEMBL14390908 | 0.80 | HPGDS (0.39) | POLBMAPTHPGDALDH1A1TNFRSF1A | |
| SCHEMBL14390695 | 0.79 | CSNK2A1 (0.43) | SMN1; SMN2NPC1RAB9APOLBMAPT | |
| SCHEMBL14390899 | 0.77 | ADORA2A (0.46) | POLBMAPTHPGDALDH1A1L3MBTL1 | |
| SCHEMBL14391013 | 0.77 | KDM4E (0.41) | NPC1RAB9APOLBHPGDALDH1A1 | |
| SCHEMBL14390693 | 0.75 | ACMSD (0.46) | HPGD | |
| SCHEMBL14391023 | 0.75 | KDM4E (0.40) | SMN1; SMN2NPC1RAB9AMAPTHPGD | |
| SCHEMBL3584180 | 0.74 | HPGDS (0.44) | SMN1; SMN2MAPTHPGDALDH1A1TNFRSF1A | |
| SCHEMBL3585765 | 0.74 | HPGDS (0.42) | SMN1; SMN2MAPTHPGDALDH1A1TNFRSF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007124546-A1 | INTEGRASE INHIBITORS 3 | AVEXA LIMITED (AU) | 2007-11-08 | — | — | WO | disclosed |