Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14391005 | 0.91 | ADORA2A (0.40) | MAPTNPC1ATMTP53RAB9A | |
| SCHEMBL3586886 | 0.88 | ALDH1A1 (0.48) | MAPTNPC1ATMTP53RAB9A | |
| SCHEMBL14391098 | 0.81 | MAPT (0.43) | MAPTNPC1ATMTP53RAB9A | |
| SCHEMBL14391010 | 0.81 | ALDH1A1 (0.43) | MAPTATMKMT2AMEN1KDM4E | |
| SCHEMBL3586638 | 0.80 | ALDH1A1 (0.48) | MAPTNPC1ATMTP53RAB9A | |
| SCHEMBL14390901 | 0.79 | PTGES (0.38) | MAPTNPC1ATMTP53RAB9A | |
| SCHEMBL3577981 | 0.77 | KMT2A (0.47) | MAPTKMT2AMEN1KDM4ESMN1; SMN2 | |
| SCHEMBL3592516 | 0.77 | ALDH1A1 (0.46) | MAPTNPC1ATMTP53RAB9A | |
| SCHEMBL14390898 | 0.76 | KMT2A (0.40) | MAPTRAB9AKMT2AMEN1KDM4E | |
| SCHEMBL3594915 | 0.76 | KMT2A (0.43) | MAPTKMT2AMEN1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007124546-A1 | INTEGRASE INHIBITORS 3 | AVEXA LIMITED (AU) | 2007-11-08 | — | — | WO | disclosed |