Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | NEK2 | P51955 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ATR | Q13535 | 2/20 | 0.37 |
| ▸ | UBE2I | P63279 | 2/20 | 0.36 |
| ▸ | SAE1 | Q9UBE0 | 2/20 | 0.36 |
| ▸ | UBA2 | Q9UBT2 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3594256 | 0.89 | HPGD (0.48) | KMT2AMEN1KDM4EMAPTALDH1A1 | |
| SCHEMBL3599184 | 0.82 | HPGD (0.42) | KMT2AMEN1KDM4EMAPTALDH1A1 | |
| SCHEMBL3592681 | 0.82 | HPGD (0.49) | KMT2AMEN1KDM4EMAPTALDH1A1 | |
| SCHEMBL3584306 | 0.81 | HPGD (0.43) | KMT2AMEN1KDM4EMAPTALDH1A1 | |
| SCHEMBL14390693 | 0.80 | ACMSD (0.46) | HPGD | |
| Tromethamine SCHEMBL3584303 | 0.79 | HPGD (0.44) | KMT2AMEN1KDM4EMAPTALDH1A1 | |
| SCHEMBL3588354 | 0.79 | ALDH1A1 (0.41) | KMT2AMEN1KDM4EMAPTALDH1A1 | |
| SCHEMBL14390901 | 0.77 | PTGES (0.38) | KMT2AMEN1KDM4EMAPTALDH1A1 | |
| SCHEMBL14391095 | 0.77 | GAA (0.39) | KMT2AMEN1KDM4EMAPTALDH1A1 | |
| SCHEMBL14391004 | 0.76 | MAPT (0.45) | KMT2AMEN1KDM4EMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007124546-A1 | INTEGRASE INHIBITORS 3 | AVEXA LIMITED (AU) | 2007-11-08 | — | — | WO | disclosed |