Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 6/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.36 |
| ▸ | RELA | Q04206 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3586484 | 0.90 | ALDH1A1 (0.41) | PTGESMEN1KMT2ARAB9AMAPT | |
| SCHEMBL3597444 | 0.81 | PTGES (0.45) | PTGESMEN1KMT2ARAB9AMAPT | |
| SCHEMBL3597438 | 0.81 | PTGES (0.45) | PTGESMEN1KMT2ARAB9AMAPT | |
| SCHEMBL14391004 | 0.79 | MAPT (0.45) | MEN1KMT2ARAB9AMAPTNPC1 | |
| SCHEMBL14390902 | 0.78 | HPGD (0.36) | PTGESMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL14391005 | 0.78 | ADORA2A (0.40) | MEN1KMT2ARAB9AMAPTNPC1 | |
| SCHEMBL3589044 | 0.77 | ALDH1A1 (0.43) | MEN1KMT2ARAB9AMAPTNPC1 | |
| SCHEMBL14390898 | 0.77 | KMT2A (0.40) | MEN1KMT2ARAB9AMAPTSMN1; SMN2 | |
| SCHEMBL14390693 | 0.74 | ACMSD (0.46) | — | |
| SCHEMBL3592516 | 0.74 | ALDH1A1 (0.46) | MEN1KMT2ARAB9AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007124546-A1 | INTEGRASE INHIBITORS 3 | AVEXA LIMITED (AU) | 2007-11-08 | — | — | WO | disclosed |