Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5403459 | 0.70 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1KDM4EHPGDMEN1 | |
| SCHEMBL10644926 | 0.70 | KIF11 (0.46) | ALDH1A1KDM4EHPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL716870 | 0.69 | TRPM8 (0.43) | ALDH1A1L3MBTL1KDM4ETRPM8CYP3A4 | |
| SCHEMBL14392999 | 0.68 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDHSD17B10MEN1 | |
| SCHEMBL31534629 | 0.67 | ALDH1A1 (0.44) | ALDH1A1KDM4EHPGDHSD17B10MEN1 | |
| SCHEMBL8064218 | 0.65 | ALDH1A1 (0.53) | ALDH1A1KDM4EHPGDHSD17B10MEN1 | |
| SCHEMBL12212071 | 0.63 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1KDM4EMEN1KMT2A | |
| SCHEMBL9112737 | 0.63 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1KDM4EHPGDMEN1 | |
| SCHEMBL9449170 | 0.63 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1KDM4EHPGDMEN1 | |
| SCHEMBL20937743 | 0.63 | ALDH1A1 (0.43) | ALDH1A1KDM4EHPGDHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007134107-A2 | COLD MENTHOL RECEPTOR-1 ANTAGONISTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-11-22 | — | — | WO | disclosed |