Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 8/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 2/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 5/20 | 0.34 |
| ▸ | GPR4 | P46093 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14394314 | 0.88 | TP53 (0.39) | SLC6A9TP53MAPTLMNAPOLB | |
| SCHEMBL13099970 | 0.87 | SLC6A9 (0.36) | SLC6A9TP53MAPTLMNAPOLB | |
| SCHEMBL14394413 | 0.86 | TP53 (0.41) | SLC6A9TP53MAPTGAALMNA | |
| SCHEMBL3065139 | 0.78 | TP53 (0.41) | SLC6A9TP53MAPTGAALMNA | |
| SCHEMBL14394153 | 0.74 | LMNA (0.39) | TP53MAPTLMNAPDE2APDE10A | |
| SCHEMBL3067316 | 0.72 | TP53 (0.42) | SLC6A9TP53MAPTGAALMNA | |
| SCHEMBL3050447 | 0.70 | TP53 (0.41) | SLC6A9TP53MAPTGAAPDE2A | |
| SCHEMBL3063113 | 0.70 | TP53 (0.44) | SLC6A9TP53MAPTGAALMNA | |
| SCHEMBL14394152 | 0.69 | ALOX5 (0.40) | PDE2APDE10A | |
| SCHEMBL3061821 | 0.69 | TP53 (0.42) | SLC6A9TP53MAPTGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7300945-B2 | Benzimidazole and pyridylimidazole derivatives | NEUROGEN CORPORATION (US) | 2007-11-27 | — | — | US | disclosed |