Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | GLP1R | P43220 | 10/20 | 0.39 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14394153 | 0.89 | LMNA (0.39) | GLP1RSOS1KCNH2PDE2APDE10A | |
| SCHEMBL13099970 | 0.80 | SLC6A9 (0.36) | PDE2APDE10A | |
| SCHEMBL3064857 | 0.79 | ALOX5 (0.39) | ALOX5GLP1RSOS1KCNH2PDE2A | |
| SCHEMBL13677369 | 0.71 | ALOX5 (0.52) | ALOX5KCNH2 | |
| SCHEMBL14394304 | 0.69 | SLC6A9 (0.42) | PDE2APDE10A | |
| SCHEMBL14394314 | 0.69 | TP53 (0.39) | PDE2APDE10A | |
| SCHEMBL3055689 | 0.66 | CYP11B2 (0.41) | GLP1RSOS1KCNH2PDE2APDE10A | |
| SCHEMBL3064551 | 0.65 | GRM5 (0.41) | GLP1RSOS1KCNH2PDE2APDE10A | |
| SCHEMBL6304436 | 0.64 | ALOX5 (0.40) | ALOX5GLP1R | |
| SCHEMBL3070587 | 0.64 | ALOX5 (0.43) | ALOX5GLP1RKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7300945-B2 | Benzimidazole and pyridylimidazole derivatives | NEUROGEN CORPORATION (US) | 2007-11-27 | — | — | US | disclosed |