Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | TOP1 | P11387 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3933161 | 0.89 | DPP4 (0.34) | BRD4DPP4 | |
| SCHEMBL3925451 | 0.79 | DPP4 (0.33) | DPP4 | |
| SCHEMBL14396494 | 0.73 | MAPK8 (0.40) | — | |
| SCHEMBL14396352 | 0.72 | SYK (0.36) | — | |
| SCHEMBL3924418 | 0.71 | OGA (0.40) | — | |
| SCHEMBL3923592 | 0.69 | DPP4 (0.37) | DPP4 | |
| SCHEMBL5914335 | 0.68 | IGF1R (0.41) | TOP1 | |
| SCHEMBL3926834 | 0.68 | LMNA (0.39) | BRD4 | |
| SCHEMBL23607243 | 0.68 | METAP2 (0.37) | BRD4DPP4 | |
| SCHEMBL5914072 | 0.63 | SQOR (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8834841-B2 | Imaging agents | EMORY UNIVERSITY (US) | 2014-09-16 | — | — | US | disclosed |
| WO-2007114827-A1 | SUBSTITUTED HETEROCYCLIC COMPOUNDS AND METHODS OF USE | AMGEN INC. (US) | 2007-10-11 | — | — | WO | disclosed |